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Trisomy 18: palliative surgical intervention
  1. Hannah Spierson1,
  2. Yasser Masood1,
  3. Ross J Craigie2,
  4. Ngozi Edi-Osagie1,3
  1. 1 Newborn Intensive Care Unit, Manchester University NHS Foundation Trust, Manchester, UK
  2. 2 Paediatric Surgery, Royal Manchester Children’s Hospital, Manchester University NHS Foundation Trust, Manchester, UK
  3. 3 Faculty of Medical and Human Science, University of Manchester, Manchester, UK
  1. Correspondence to Dr Hannah Spierson, Newborn Intensive Care Unit, Manchester University NHS Foundation Trust, Manchester M23 9LT, UK; hannahspierson{at}

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Trisomy 18 has a poor prognosis,1 2 however, some of the anomalies seen may be amenable to surgery in the neonatal period, therefore providing intensive care including surgery must be carefully considered. We undertook a retrospective review of surgical intervention in babies with a confirmed diagnosis of Trisomy 18 admitted to our neonatal unit over a 5-year period (1 September 2011 to 31 August 2016). Fifteen babies with Trisomy 18 were identified, 12 male and 3 female. Mean maternal age at delivery was 36 years (range 22–45 years). Mean birth weight was 1.91 kg (range 1.02–2.85 kg). Babies were born …

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  • Contributors NEO provided the concept. HS and YM collected the data and drafted the paper. RJC and NEO revised the draft paper.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

  • Presented at The paper ‘Masood Y, Spiers H, Cragie R, Edi-Osagie N. Surgical intervention in trisomy 18—supporting pallative care. Archives of Disease in Childhood, 102, pp A202–3’ is presented at the Annual Conference of the Royal College of Paediatrics and Child Health (RCPCH), 2017, UK.