Online First

August 08, 2022

August 05, 2022

August 02, 2022

July 28, 2022

July 27, 2022

  • Paediatric Emergency Medicine
    Rate of invasive bacterial infection in recently vaccinated young infants with fever without source
    Ana Barreiro-Parrado, Eider Lopez, Borja Gomez, Ainara Lejarzegi, Amaia Fernandez-Uria, Javier Benito, Santiago Mintegi

    This secondary analysis of observational registry data compared the rates of IBI (bacterial pathogen in blood or cerebrospinal fluid) and urinary tract infection (UTI) in febrile infants between 42 and 90 days of age who had and had not been vaccinated in the previous 48 hours and conclude that UTI screening remains appropriate, but with further study the need for IBI screening in recently vaccinated infants could be revisited.

July 26, 2022

July 22, 2022

July 21, 2022

July 20, 2022

  • Original research
    Community seroprevalence of SARS-CoV-2 in children and adolescents in England, 2019–2021
    Helen Ratcliffe, K S Tiley, Nick Andrews, Gayatri Amirthalingam, I Vichos, E Morey, N L Douglas, S Marinou, Emma Plested, Parvinder Aley, Eva P Galiza, Saul N Faust, S Hughes, Clare S Murray, Marion Roderick, Fiona Shackley, Sam J Oddie, Tim Lees, D P J Turner, M Raman, Stephen Owens, Paul Turner, H Cockerill, J Lopez Bernal, E Linley, Ray Borrow, Kevin Brown, Mary Elizabeth Ramsay, M Voysey, Matthew D Snape

    How many children have antibody to COVID-19 before they are vaccinated? This community seroprevalance study finds about a third of children with antibody to COVID (although this varies by age and ethnicity). In children <10-years there were no symptoms or symptom clusters that reliably predicted seropositivity.

July 19, 2022

  • Images in paediatrics
    Unusual cause of ‘croup’
    Emily Pye, Charlotte Lucy Durand, Anne Kerr, Adam J Donne

July 18, 2022

  • Original research
    Trends in weight loss attempts among children in England
    Aryati Ahmad, Melissa Little, Carmen Piernas, Susan Jebb

    Paper describe trends in reported weight loss attempts among school-aged children. 34,235 children were analysed. Weight loss attempts among children is increasing at a faster rate than the rise in excess weight and includes an increasing proportion of children with a ‘healthy’ weight.

  • Review
    Beyond arrival: safeguarding unaccompanied asylum-seeking children in the UK
    Nuria Sanchez-Clemente, Sarah Eisen, Christian Harkensee, Nicky Longley, Rob O'Grady, Allison Ward
  • Original research
    Discharge outcome analysis of 1089 transgender young people referred to paediatric endocrine clinics in England 2008–2021
    Gary Butler, Kirpal Adu-Gyamfi, Kerry Clarkson, Ranna El Khairi, Sara Kleczewski, Alice Roberts, Terry Y Segal, Karththeepan Yogamanoharan, Sabah Alvi, Nadia Amin, Paul Carruthers, Stacey Dover, Joanna Eastman, Talat Mushtaq, Una Masic, Polly Carmichael

    This paper reports post-discharge outcomes of a large national cohort of transgender and gender variant young people who were referred by the NHS Gender Identity Development Service (GIDS) to, and discharged from, the two English NHS paediatric endocrine liaison centres clinics.

  • Review
    Contemporary paediatric radiation oncology
    Tom Boterberg, Cathy Dunlea, Semi Harrabi, Geert Janssens, Anne Laprie, Gillian Whitfield, Mark Gaze on behalf of the SIOP-Europe Radiation Oncology Working Group
  • Original research
    Evolution of paediatric eating disorders in Singapore: a historical cohort study
    Lisa Wong, Lee Gan Goh, Rajeev Ramachandran

    An epidemiological study depicting the evolution of paediatric eating disorders over the last 30 years in Singapore and the region.

July 15, 2022

  • Original research
    Early weight gain influences duration of breast feeding: prospective cohort study
    Laurentya Olga, Janna A van Diepen, Gabriele Gross, David B Dunger, Ken K Ong

    In this longitudinal cohort study of term, singleton, normal birthweight, initially exclusively breastfed infants, slower weight gain while exclusively breast feeding was associated with higher likelihood of introduction of infant milk formula in subsequent follow-up periods, between 2 and 11 weeks.

  • Images in paediatrics
    Calciphylaxis in an adolescent without renal failure
    Moeinadin Safavi, Payman Sadeghi, Shima Hosseinlou

July 13, 2022

July 08, 2022

July 06, 2022

  • Original research
    Postoperative morbidities with infant cardiac surgery and toddlers’ neurodevelopment
    Julie Read, Deborah Ridout, Samantha Johnson, Aparna Hoskote, Karen Sheehan, Paul Wellman, Alison Jones, Jo Wray, Katherine Brown

    A multi-centre followup study evaluating neurodevelopmental outcomes of children aged 2-3 years who underwent infant cardiac surgery and experienced post-operative morbidities compared to matched controls who did not have complications.

June 30, 2022

  • Original research
    Diabetic ketoacidosis fluid management in children: systematic review and meta-analyses
    Ali Abdalla Hamud, Khalid Mudawi, Ahmed Shamekh, Ayodeji Kadri, Colin Powell, Ibtihal Abdelgadir

    This review and metanalysis of fluid management in paediatric diabetic ketoacidosis found no evidence that the rate of fluid administration has any effect on clinical outcomes or length of stay.

June 29, 2022

  • Original research
    Factors that may improve paediatric workplace-based assessments: an exploratory study
    Kimberley Jefferies

    By using semi-structured interviews, this study looks at trainees’ and assessors’ views of workplace-based assessments, identifying time, training and limitations of technology as barriers to completion.

  • Original research
    Paediatric health-related quality of life in congenital cytomegalovirus
    Kate Monica Isabel Ralph, Kim Bull, Caroline Trotter, Sharon Wood, Christine E Jones

    What is the Health Related Quality of life (HRQoL) for children with congenital CMV (cCMV) infection and their parents?This study found cCMV has a significant effect on the HRQoL of children with cCMV and their parents, with the children with the most significant health needs having the lowest HRQoL compared to those children with little or no effects on their health.This information could help assess the possible benefits of screening for cCMV.

June 28, 2022

June 27, 2022

June 22, 2022

  • Original research
    Advanced chronic kidney disease among UK children
    Lucy Plumb, Winnie Magadi, Anna Casula, Ben C Reynolds, Mairead Convery, Shuman Haq, Shivaram Hegde, Andrew Lunn, Michal Malina, Henry Morgan, Mordi Muorah, Kay Tyerman, Manish D Sinha, Dean Wallace, Carol Inward, Stephen Marks, Dorothea Nitsch, James Medcalf

June 21, 2022

June 20, 2022

June 16, 2022

June 15, 2022

  • Review
    What is new in migraine management in children and young people?
    Ne Ron Loh, William P Whitehouse, Rachel Howells
  • Original research
    Prevalence of SARS-CoV-2 positivity in infants with bronchiolitis: a multicentre international study
    Giorgio Cozzi, Luisa Cortellazzo Wiel, Alessandro Amaddeo, Antonio Gatto, Manuela Giangreco, Adi Klein-Kremer, Samantha Bosis, Davide Silvagni, Carla Debbia, Laura Nanni, Sara Chiappa, Marta Minute, Ilaria Corsini, Giuliana Morabito, Anna Jolanda Gortan, Marco Colombo, Federico Marchetti, Davide Garelli, Arianna Piffer, Fabio Cardinale, Nitai Levy, Antonietta Curatola, Bojana Gojsina, Suvradeep Basu, Egidio Barbi, Aleksandar Sovtic On behalf of the SARS-CoV-2 bronchiolitis study group

    During the SARS-CoV-2 pandemic, very few infants with SARS-CoV-2 had bronchiolitis and mostly displayed a mild clinical course. Overall there was a marked decrease in bronchiolitis cases, indeed the RSV winter epidemic did not occur.

June 14, 2022

June 10, 2022

  • Original research
    Oral saliva swab reverse transcription PCR for Covid-19 in the paediatric population
    Cinta Moraleda, Sara Domínguez-Rodríguez, Juan Miguel Mesa, Paula García-Sánchez, María de la Serna, José Antonio Alonso-Cadenas, Amanda Bermejo, Gema Sabrido, Leticia Martínez-Campos, Aránzazu Flavia González-Posada, Marta Illán-Ramos, Elena Cobos-Carrascosa, Álvaro Ballesteros, Juan Carlos Galán, Francisco Llorente, David Aguilera-Alonso, Ana Belén Jiménez, Pilar Catalán, Elias Dahdouh, Ignacio Navarro, Bárbara Fernández-Garoz, Pablo Mendoza, Concepción Pérez-Jorge, Teresa Cabezas-Fernández, Daniel Blázquez-Gamero, Gonzalo Rivas, Patricia Gonzalez-Donapetry, Elena Sáez, Jovita Fernández-Pinero, Jesús Lucas-Fernández, Elisa Pérez-Ramírez, Paloma Merino, Sandra Miragaya, Jorge Lorente, Irene Iglesias, Alfredo Tagarro the EPICO working group

    The results from this multi-centre prospective diagnostic test accuracy study suggest that molecular testing of oral saliva samples for SARS-CoV-2 in children is an accurate and less invasive alternative to molecular testing of nasopharyngeal/oropharyngeal swabs.

June 09, 2022

June 08, 2022