Online First

July 06, 2022

  • Original research
    Postoperative morbidities with infant cardiac surgery and toddlers’ neurodevelopment
    Julie Read, Deborah Ridout, Samantha Johnson, Aparna Hoskote, Karen Sheehan, Paul Wellman, Alison Jones, Jo Wray, Katherine Brown

    A multi-centre followup study evaluating neurodevelopmental outcomes of children aged 2-3 years who underwent infant cardiac surgery and experienced post-operative morbidities compared to matched controls who did not have complications.

June 30, 2022

  • Original research
    Diabetic ketoacidosis fluid management in children: systematic review and meta-analyses
    Ali Abdalla Hamud, Khalid Mudawi, Ahmed Shamekh, Ayodeji Kadri, Colin Powell, Ibtihal Abdelgadir

    This review and metanalysis of fluid management in paediatric diabetic ketoacidosis found no evidence that the rate of fluid administration has any effect on clinical outcomes or length of stay.

June 29, 2022

  • Original research
    Factors that may improve paediatric workplace-based assessments: an exploratory study
    Kimberley Jefferies

    By using semi-structured interviews, this study looks at trainees’ and assessors’ views of workplace-based assessments, identifying time, training and limitations of technology as barriers to completion.

  • Archivist
    Research priorities in inpatient general paediatrics
  • Original research
    Paediatric health-related quality of life in congenital cytomegalovirus
    Kate Monica Isabel Ralph, Kim Bull, Caroline Trotter, Sharon Wood, Christine E Jones

    What is the Health Related Quality of life (HRQoL) for children with congenital CMV (cCMV) infection and their parents?This study found cCMV has a significant effect on the HRQoL of children with cCMV and their parents, with the children with the most significant health needs having the lowest HRQoL compared to those children with little or no effects on their health.This information could help assess the possible benefits of screening for cCMV.

June 28, 2022

June 27, 2022

June 22, 2022

  • Original research
    Advanced chronic kidney disease among UK children
    Free
    Lucy Plumb, Winnie Magadi, Anna Casula, Ben C Reynolds, Mairead Convery, Shuman Haq, Shivaram Hegde, Andrew Lunn, Michal Malina, Henry Morgan, Mordi Muorah, Kay Tyerman, Manish D Sinha, Dean Wallace, Carol Inward, Stephen Marks, Dorothea Nitsch, James Medcalf

June 21, 2022

June 20, 2022

June 16, 2022

June 15, 2022

  • Review
    What is new in migraine management in children and young people?
    Ne Ron Loh, William P Whitehouse, Rachel Howells
  • Original research
    Prevalence of SARS-CoV-2 positivity in infants with bronchiolitis: a multicentre international study
    Free
    Giorgio Cozzi, Luisa Cortellazzo Wiel, Alessandro Amaddeo, Antonio Gatto, Manuela Giangreco, Adi Klein-Kremer, Samantha Bosis, Davide Silvagni, Carla Debbia, Laura Nanni, Sara Chiappa, Marta Minute, Ilaria Corsini, Giuliana Morabito, Anna Jolanda Gortan, Marco Colombo, Federico Marchetti, Davide Garelli, Arianna Piffer, Fabio Cardinale, Nitai Levy, Antonietta Curatola, Bojana Gojsina, Suvradeep Basu, Egidio Barbi, Aleksandar Sovtic On behalf of the SARS-CoV-2 bronchiolitis study group

    During the SARS-CoV-2 pandemic, very few infants with SARS-CoV-2 had bronchiolitis and mostly displayed a mild clinical course. Overall there was a marked decrease in bronchiolitis cases, indeed the RSV winter epidemic did not occur.

June 14, 2022

June 10, 2022

  • Original research
    Oral saliva swab reverse transcription PCR for Covid-19 in the paediatric population
    Free
    Cinta Moraleda, Sara Domínguez-Rodríguez, Juan Miguel Mesa, Paula García-Sánchez, María de la Serna, José Antonio Alonso-Cadenas, Amanda Bermejo, Gema Sabrido, Leticia Martínez-Campos, Aránzazu Flavia González-Posada, Marta Illán-Ramos, Elena Cobos-Carrascosa, Álvaro Ballesteros, Juan Carlos Galán, Francisco Llorente, David Aguilera-Alonso, Ana Belén Jiménez, Pilar Catalán, Elias Dahdouh, Ignacio Navarro, Bárbara Fernández-Garoz, Pablo Mendoza, Concepción Pérez-Jorge, Teresa Cabezas-Fernández, Daniel Blázquez-Gamero, Gonzalo Rivas, Patricia Gonzalez-Donapetry, Elena Sáez, Jovita Fernández-Pinero, Jesús Lucas-Fernández, Elisa Pérez-Ramírez, Paloma Merino, Sandra Miragaya, Jorge Lorente, Irene Iglesias, Alfredo Tagarro the EPICO working group

    The results from this multi-centre prospective diagnostic test accuracy study suggest that molecular testing of oral saliva samples for SARS-CoV-2 in children is an accurate and less invasive alternative to molecular testing of nasopharyngeal/oropharyngeal swabs.

June 09, 2022

June 08, 2022

May 23, 2022

  • Global child health
    Training packages for the use of child development tools in low/middle-income countries: a review
    Free
    Maria Neocleous, Katelyn Hepworth, Vanessa Cavallera, Melissa Gladstone

    Essential to improvements in overall child health is an emphasis on helping children thrive as well as survive. This new emphasis will require a well-trained healthcare workforce in this regard. This paper reviews child development training packages in resource-limited settings.

May 20, 2022

May 18, 2022

  • Global child health
    Higher childhood pneumonia admission threshold remains in Lao PDR: an observational study
    Free
    Ruth Lim, Molina Chaummanivong, Chansathit Taikeophithoun, Amy Gray, Adam W J Jenney, Vanphanom Sychareun, Cattram Nguyen, Fiona Russell

    This study from Lao assesses adherence to the simplified, less parenteral antibiotic focused WHO 2014 pneumonia guidance compared with earlier recommendations.

May 16, 2022

  • Original research
    Oral and Swallowing Abilities Tool (OrSAT) in nusinersen treated patients
    Beatrice Berti, Lavinia Fanelli, Giulia Stanca, Roberta Onesimo, Concetta Palermo, Daniela Leone, Roberto de Sanctis, Sara Carnicella, Giulia Norcia, Nicola Forcina, Giorgia Coratti, Maria Carmela Pera, Valentina Giorgio, Carolina Ausili Cefaro, Richard Finkel, Marika Pane, Eugenio Mercuri

    New interventions have radically altered the natural history of Spinal Muscular Atrophy. In this report, oral and swallowing outcomes are report following interventions, widening our understanding of the potential benefits of early treatment.

  • Original research
    Changes in adolescents’ planned hospital care during the COVID-19 pandemic: analysis of linked administrative data
    Louise Mc Grath-Lone, David Etoori, Ruth Gilbert, Katie L Harron, Jenny Woodman, Ruth Blackburn

    This paper describes changes in planned hospital care for adolescents during the pandemic, highlighting the disproportionate impact on those receiving children’s social care services or special educational needs support.

May 12, 2022

  • Review
    Being involved: what RCPCH does for members and vice versa
    Steve Turner
  • Original research
    Diet and development among children aged 36–59 months in low-income countries
    Lilia Bliznashka, Nandita Perumal, Aisha Yousafzai, Christopher Sudfeld

    This detailed analysis of Demographic and Health Survey data from children in 15 LMICs demonstrates remarkable connections between diet and cognitive development.

  • Original research
    Do you know when the inhaler is empty?
    I Fullwood, T Evans, Benjamin Davies, T Ninan, C Onyon, J Clarke, Rajesh Srikanthiah, Susan Frost, N Iqbal, M Atkinson, Satish Rao, Prasad Nagakumar

    Patients cannot reliably identify when their child’s inhaler is empty. There is an urgent need for improving inhaler technology and providing appropriate guidance on how to identify when an MDI inhaler is empty.

May 10, 2022

  • Letter
    Myanmar paediatricians during military coup: we strike and survive
    Free
    Thet Htar Shwe Sin Win, Myint Me Me, Wah Wah Winn, Kaung Myat Kyaw
  • Paediatric Emergency Medicine
    Outpatient parenteral antimicrobial therapy: how young is too young?
    Kate Alison Hodgson, Ruth Lim, Julie Huynh, Ben Nind, Naomi Katz, Robin Marlow, Conor C Hensey, Barry Scanlan, Laila F Ibrahim, Penelope A Bryant

    A prospective 8-year observational study from September 2012 to September 2020 including 76 episodes for which neonates were admitted to the Hospital-in-the-Home (HITH) for outpatient parenteral antimicrobial therapy (OPAT), and 405 episodes for older infants evaluated the use, the efficacy and the outcomes of OPAT in neonates (≤28 days of age), compared with older infants (1-12 months of age). This study demonstrates that OPAT is a safe and effective way of providing antibiotics to selected clinically stable neonatal patients. Whilst appropriate antibiotic use was common, improvements can still be made.

  • Archimedes
    Is recombinant tissue plasminogen activator treatment a safe choice in very and extremely preterm infants with intracardiac thrombosis?
    Martina Ciarcià, Iuri Corsini, Francesca Miselli, Michele Luzzati, Caterina Coviello, Valentina Leonardi, Simone Pratesi, Carlo Dani
  • Original research
    Short-course intravenous antibiotics for young infants with urinary tract infection
    Jolie Lawrence, Laure F Pittet, Samar Hikmat, Eloise J Silvester, Vanessa Clifford, Rodney Hunt, Amanda Gwee

    This study aimed to determine the safety of early IV-to-oral antibiotic switch, and identify risk factors for bacteraemia with UTIs. Short course IV antibiotics for <48 hours for young infants with non-bacteraemic UTI should be considered, provided meningitis has been excluded. Treatment failure and serious complications were rare in young infants with UTI.

May 09, 2022

May 05, 2022

May 02, 2022

  • Original research
    Gestational age and risk of intellectual disability: a population-based cohort study
    Weiyao Yin, Nora Döring, Monica S M Persson, Martina Persson, Kristina Tedroff, Ulrika Ådén, Sven Sandin

    In this large retrospective study, the authors explore the relationship between gestational age on a week-by-week basis and the risk of intellectual disability. This analysis provides further evidence of the potential adverse consequences of even moderate prematurity

April 27, 2022

April 25, 2022

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