Online First

May 14, 2021

May 13, 2021

  • Original research
    Listeria infection in young infants: results from a national surveillance study in the UK and Ireland
    Stefania Vergnano, Gauri Godbole, Ameze Simbo, Alison Smith-Palmer, Martin Cormican, Anthony Mark, Paul T Heath

    Who needs empirical treatment for Listeria infection? This national surveillance study found that invasive listeriosis in young infants in the UK and Ireland is rare and presented only in the neonatal period. Use of amoxicillin as part of empiric treatment for sepsis and meningitis in infants over 1 month of age may be unnecessary.

May 12, 2021

May 11, 2021

  • Letter
    Foreign body ingestion in children: a magnet epidemic within a pandemic
    Hemanshoo Thakkar, Katherine Mary Burnand, Costa Healy, Erica Makin, Joseph Davidson, George Bethell, Hesham Elagami, Alexandra Scarlett, Shabnam Parkar, Manasvi Upadhyaya, Iain Yardley On behalf of the Quadri-South East Paediatric Surgeons (QuadriSEPS) Group
  • Review
    Paediatric narcolepsy: a review of diagnosis and management
    Jane Elizabeth Blackwell, Ruth N Kingshott, Anna Weighall, Heather E Elphick, Hannah Nash

    The authors present a comprehensive review of narcolepsy in childhood, including details on our current understanding of pathophysiology, how to investigate a child when a diagnosis is suspected and suggestions for management.

  • Original research
    Novel strategy to personalise use of ibuprofen for closure of patent ductus arteriosus in preterm neonates
    Samira Samiee-Zafarghandy, Tamara van Donge, Gerhard Fusch, Marc Pfister, George Jacob, Andrew Atkinson, Michael J Rieder, Cornelis Smit, John Van Den Anker

    This study examines the pharmacokinetics of ibuprofen given to neonates for patent ductus arteriosus closure. Low concentrations of ibuprofen can be identified, which moves studies comparing individualised dosing a step closer.

May 07, 2021

May 06, 2021

  • Original research
    Medication discrepancies in transition of care of hospitalised children in Brazil: a multicentric study
    Giulyane Targino Aires-Moreno, Thaciana dos Santos Alcântara, Dyego Carlos Souza Anacleto de Araújo, Simony da Mota Soares, Vanessa Terezinha Gubert, Vanessa Marcon de Oliveira, Cristiane Munaretto Ferreira, Erica Freire Vasconcelos-Pereira, Ana Rafaela Pires Lira, Clarice Chemello, Layse Maria Soares de Oliveira, Alfredo Dias de Oliveira-Filho, Divaldo Lyra Jr

    Accurate medication reconciliation is important, and this 4 centre study from Brasil shows the prevalence and significance of omissions, both unintentional and intentional.

  • Review
    Bibliography of published COVID-19 in children literature
    Philippa Anna Stilwell, Alasdair P. S. Munro, Emre Basatemur, Nishanthi Talawila Da Camara, Rachel Harwood, Damian Roland

    A paper that describes the dynamic changes in global volume of literature relating to Covid-19 in children and young people published over the first six months of the pandemic. Two thirds of all papers published described just nine patients or fewer.

May 05, 2021

May 03, 2021

April 30, 2021

  • Archimedes
    Does early egg introduction prevent egg allergy in children?
    Viktorija Kaminskaite, Sian Ludman
  • Images in paediatrics
    Interesting case of traumatic paediatric chest pain: don’t forget the vessels
    Matthew G W Macartney, Nick Clarke, Julie-Ann Collins, Stephen Mullen
  • Images in paediatrics
    Hyperpigmented pityriasis versicolor misdiagnosed as acanthosis nigricans
    Benedetta Bossini, Michele Mazzolai, Irene Berti, Egidio Barbi
  • Short report
    Prevalence of thrombotic complications in children with SARS-CoV-2
    David Aguilera-Alonso, Sara Murias, Amelia Martínez-de-Azagra Garde, Antoni Soriano-Arandes,, Marta Pareja, Enrique Otheo, Cinta Moraleda, Alfredo Tagarro, Cristina Calvo on behalf of EPICO-AEP Working Group

    A very timely paper on the Spanish experience of SARS-CoV-2. Over 500 infected children from 49 hospitals across Spain were recorded between 1st March - 30th Sept 2020, with 4 cases of thrombosis (1.1% of hospitalised cases). Half had thrombotic risk factors, 3/4 were adolescent females. Authors to be commended for collecting and collating these data during this difficult time, so providing our readers with some valuable insights into the incidence of thrombosis.

  • Original research
    Growth and adrenarche: findings from the CATS observational study
    Anne-Lise Goddings, Russell M Viner, Lisa Mundy, Helena Romaniuk, Charlotte Molesworth, John B Carlin, Nicholas B Allen, George C Patton

    This cross sectional study of 1151 children aged 8-9 years found an association between BMI and waist circumference and raised androgen concentrations that was independent of age and sex.

  • Original research
    Decision-making for children requiring interhospital transport: assessment of a novel triage tool
    Anthony Slater, Deanne Crosbie, Dionne Essenstam, Brett Hoggard, Paul Holmes, Julie McEniery, Michelle Thompson

    Deciding on interhospital transport of unwell and potentially critically ill children is not necessarily straightforward. The authors describe a new tool to help decision making and communication in this process.

April 27, 2021

April 21, 2021

  • Original research
    Intimate partner violence and child outcomes at age 10: a pregnancy cohort
    Deirdre Gartland, Laura J Conway, Rebecca Giallo, Fiona K Mensah, Fallon Cook, Kelsey Hegarty, Helen Herrman, Jan Nicholson, Sheena Reilly, Harriet Hiscock, Emma Sciberras, Stephanie J Brown

    In an Australian pregnancy cohort, maternal report of intimate partner violence is associated with poorer physical and mental health outcomes for their children at age 10 years.

April 20, 2021

April 16, 2021

  • Original research
    Feeding disorders in children with oesophageal atresia: a cross-sectional study
    Aurélie Pham, Emmanuelle Ecochard-Dugelay, Arnaud Bonnard, Enora Le Roux, Thomas Gelas, Véronique Rousseau, Nadège Thomassin, Isabelle Cabon-Boudard, Audrey Nicolas, Audrey Guinot, Julie Rebeuh, Aurélie Le Mandat, Djamal-Dine Djeddi, Virginie Fouquet, Aurélie Boucharny, Sabine Irtan, Julie Lemale, Aurélie Comte, Laure Bridoux-Henno, Claire Dupont-Lucas, Georges Dimitrov, Anne Turquet, Corinne Borderon, Cécile Pelatan, Emilie Chaillou Legault, Camille Jung, Stéphanie Willot, Louise Montalva, Delphine Mitanchez, Frederic Gottrand, Marc Bellaiche

    This study of patients from the French national network oesophageal atresia (OA) registry used a standardised questionnaire to investigate the frequency of feeding disorders. These were diagnosed in 42%, of whom over a third had failed to thrive. The authors advocate systematic feeding assessment in follow up of children operated on for OA.

April 15, 2021

April 14, 2021

April 12, 2021

April 08, 2021

April 07, 2021

March 30, 2021

March 19, 2021

  • Original research
    Experiences of adolescents living with Silver-Russell syndrome
    Lisa Marie Ballard, Elizabeth Jenkinson, Christopher D Byrne, Jenny C Child, Hazel Inskip, Oluwakemi Lokulo-Sodipe, Deborah J G Mackay, Emma L Wakeling, Justin Huw Davies, I Karen Temple, Angela Fenwick

    In depth qualitative interviews with young people growing up with Silver- Russell syndrome identified multiple psychosocial challenges. Currently young people are discharged and not monitored into adulthood. This may need to change

March 18, 2021

  • Original research
    Sharing a household with children and risk of COVID-19: a study of over 300 000 adults living in healthcare worker households in Scotland
    Rachael Wood, Emma Thomson, Robert Galbraith, Ciara Gribben, David Caldwell, Jennifer Bishop, Martin Reid, Anoop S V Shah, Kate Templeton, David Goldberg, Chris Robertson, Sharon J Hutchinson, Helen M Colhoun, Paul M McKeigue, David A McAllister

    Many parents know that having young children in the house means they get frequent respiratory viral infections. Is this the same for COVID, which is less frequent and less severe in children? This cohort study finds that having young children in the house reduces the risk of COVID.

March 16, 2021

  • Original research
    Post-COVID-19 paediatric inflammatory multisystem syndrome: association of ethnicity, key worker and socioeconomic status with risk and severity
    Jonathan Broad, Julia Forman, James Brighouse, Adebola Sobande, Alysha McIntosh, Claire Watterson, Elizabeth Boot, Felicity Montgomery, Iona Gilmour, Joy Tan, Mary Johanna Fogarty, Xabier Gomez, Ronny Cheung, Jon Lillie, Vinay Shivamurthy, Jenny Handforth, Owen Miller PIMS-TS study group

    In a cohort of children from South East England, there was some evidence for potentially higher risk & severity in groups with higher deprivation and in ethnic minoritys. The finding warrant further investigation.

  • Original research
    Risk factors for intellectual disability in children with spastic cerebral palsy
    David Cummins, Claire Kerr, Karen McConnell, Oliver Perra

    Using valuable data from the Northern Ireland Cerebral Palsy (CP) Register collected over more then 20 years, the authors demonstrate that severe intellectual disability is more common in children with bilateral compared to unilateral cerebral CP, with a greater risk in children born near term. As well as guiding the focus of screening for such problems in this population, this serves to demonstrate the value of well curated registry data for children with CP.

  • Original research
    Influence of agents and mechanisms of injury on anatomical burn locations in children <5 years old with a scald
    Assim Ali Javaid, Emma Johnson, Linda Hollén, Alison Mary Kemp

    This cross-sectional study collected standardised data from 20 hospital sites in England and Wales on over 1000 children presenting acutely with scalds. Mechanisms of injury and distribution of scalds are described, with data on referrals to child protection agencies.

  • Letter
    Prevalence and sources of tension in paediatric inpatient care
    Ceit Jesmont, Katy Wood, Chris O'Brien, Yincent Tse

March 12, 2021

March 11, 2021

  • Short report
    Bronchiolitis and SARS-CoV-2
    Gregorio Paolo Milani, Valentina Bollati, Luca Ruggiero, Samantha Bosis, Raffaella Maria Pinzani, Giovanna Lunghi, Federica Rota, Laura Dioni, Anna Luganini, Carlo Agostoni, Paola Marchisio

    SARS-CoV-2 was not already circulating among infants with bronchiolitis and asymptomatic infants before the official outbreak of SARS-CoV-2 before February 2020.There is an association between SARS-CoV-2 and bronchiolitis