Online First

August 04, 2021

August 02, 2021

July 27, 2021

July 26, 2021

  • Original research
    Palliative care for children with complex cardiac conditions: survey results
    Sidharth Vemuri, Ashleigh E Butler, Katherine Brown, Jo Wray, Myra Bluebond-Langner

    There is perceived underutilisation of palliative care practitioners in UK paediatric cardiac care. This 2018 UK wide e-survey explores this, confirms it & suggests a more integrated approach with increased training of cardiac practitioners & more embedded palliative care practitioners, before end of life if at all possible.

July 22, 2021

July 21, 2021

July 20, 2021

  • Original research
    Care bundles to reduce unplanned extubation in critically ill children: a systematic review, critical appraisal and meta-analysis
    Paulo Sergio Lucas da Silva, Maria Eunice Reis, Daniela Farah, Teresa Raquel M Andrade, Marcelo Cunio Machado Fonseca

    Review to understand the evidence base for care bundles ie doing multiple improvements at once in children who are intubated to try and prevent unexpected extubation.

  • Original research
    Impact of the COVID-19 pandemic on routine childhood immunisation in Colombia
    Jose Moreno-Montoya, Silvia Marcela Ballesteros, Jaid Constanza Rojas Sotelo, Clara Lucia Bocanegra Cervera, Pedro Barrera-López, José A De la Hoz-Valle

    This population-based study showed that during the first six months of the COVID-19 pandemic, there was a 14% absolute reduction in early childhood immunizations among Columbian children compared to the same period during 2019. Children living in rural regions of Columbia were disproportionately affected.

  • Original research
    Infant Escherichia coli urinary tract infection: is it associated with meningitis?
    Aisling Rafferty, Richard J Drew, Robert Cunney, Désirée Bennett, John Francis Marriott

    Using a retrospective cohort design, the authors sought to determine the prevalence of co-existing bacterial meningitis in infants and young children in the presence of Escherichia coli urinary tract infection. In 314 patients with UTI and an LP performed, no cases of co-existing E. coli meningitis were identified.

July 19, 2021

July 16, 2021

July 15, 2021

July 13, 2021

  • Quality improvement
    Impact of a standardised parenteral nutrition protocol: a quality improvement experience from a NICU of a developing country
    Gul Ambreen, Vikram Kumar, Syed Rehan Ali, Uswa Jiwani, Waqar Khowaja, Ali Shabbir Hussain, Kashif Hussain, Syed Shamim Raza, Arjumand Rizvi, Uzair Ansari, Khalil Ahmad, Simon Demas, Shabina Ariff

    Standardised parenteral nutrition formulations are widely used in neonatal intensive care for convenience and safety. This retrospective investigation compares individualised versus standardised feeds in a LMIC setting, in the context of a a quality improvement study. Use of standardised feeds made on site was a feasible alternative to individualised prescription.

July 09, 2021

July 08, 2021

July 06, 2021

July 02, 2021

June 30, 2021

June 29, 2021

  • Original research
    Shock Index in the early assessment of febrile children at the emergency department: a prospective multicentre study
    Nienke N Hagedoorn, Joany M Zachariasse, Dorine Borensztajn, Elise Adriaansens, Ulrich von Both, Enitan D Carrol, Irini Eleftheriou, Marieke Emonts, Michiel van der Flier, Ronald de Groot, Jethro Adam Herberg, Benno Kohlmaier, Emma Lim, Ian Maconochie, Federico Martinón-Torres, Ruud Gerard Nijman, Marko Pokorn, Irene Rivero-Calle, Maria Tsolia, Dace Zavadska, Werner Zenz, Michael Levin, Clementien Vermont, Henriette A Moll On behalf of the PERFORM consortium

    EU multicentre ED study of presenting vital signs in >5000 febrile children with an association between "shock index" and serious illness, but low sensitivity limits utility in screening.

  • Original research
    Childhood seizures after prenatal exposure to maternal influenza infection: a population-based cohort study from Norway, Australia and Canada
    Laura L Oakley, Annette K Regan, Deshayne B Fell, Sarah Spruin, Inger Johanne Bakken, Jeffrey C Kwong, Gavin Pereira, Natasha Nassar, Kari M Aaberg, Allen J Wilcox, Siri E Håberg

    This registry based study demonstrates a link between seizures in childhood and prenatal exposure to maternal influenza. This relationship was strong for febrile seizures, but not statistically significant for children with epilepsy.

June 28, 2021

June 22, 2021

  • Short report
    Delivering tertiary tuberculosis care virtually
    Louise Turnbull, Christine Bell, Stefanie Davies, Fran Child

    A weekly virtual clinic with MDT discussion between between district paediatricians and a tertiary TB team showed that:45% children received care closer to home. Median time from presentation to treatment reduced by 28%. 21% more children diagnosed before developing symptoms.

June 21, 2021

June 17, 2021

  • Clinical law for clinical practice
    Providing beds for children
    Robert Wheeler
  • Original research
    Impaired grip strength in children with congenital heart disease
    Michael Meyer, Yi Wang, Leon Brudy, Anna-Luisa Häcker, Thorsten Schulz, Heidi Weberruss, Renate Oberhoffer, Peter Ewert, Jan Müller

    Physical fitness is an important aspect of wellness. In 569 long term survivors of CHD surgery both grip strength & health-related physical fitness (a 5 parameter composite) were reduced but the reductions were unrelated. Grip strength is easily assessed but is not a surrogate for the more complex tool.

  • Original research
    Listeria infection in young infants: results from a national surveillance study in the UK and Ireland
    Stefania Vergnano, Gauri Godbole, Ameze Simbo, Alison Smith-Palmer, Martin Cormican, Mark Anthony, Paul T Heath

    Who needs empirical treatment for Listeria infection? This national surveillance study found that invasive listeriosis in young infants in the UK and Ireland is rare and presented only in the neonatal period. Use of amoxicillin as part of empiric treatment for sepsis and meningitis in infants over 1 month of age may be unnecessary.

  • Letter
    Ethiopian paediatric oncology registry progress report: documentation practice improvements at tertiary care centre in Addis Ababa, Ethiopia
    Scott Levy, Atalay Mulu Fentie, Kaitlyn Buhlinger, Stephen M Clark, David N Korones, Vanessa Miller, Thomas B Alexander, Sheila Weitzman, Wondwessen Bekele, Julie Broas, Aziza Shad, Megan Roberts, Michael Chargualaf, Diriba Fufa, Tadele Hailu, Mulugeta Ayalew Yimer, Mohammed Mustefa, Abdulkadir M Said Gidey, Ali Mamude Dinkiye, Haileyesus Adam, Daniel Hailu, Benyam Muluneh

June 16, 2021

  • Original research
    Prevalence of monogenic disease in paediatric patients with a predominant respiratory phenotype
    Dan Dai, Mei Mei, Liyuan Hu, Yun Cao, Xiaochuan Wang, Libo Wang, Yulan Lu, Lin Yang, Xinran Dong, Huijun Wang, Bingbing Wu, Liling Qian

    This manuscript reports on the prevalence and clinical characteristics of monogenic disease in paediatric patients with a predominant respiratory phenotype. And that exam sequencing is a valuable tool for this with 140 positive cases in a cohort of 971.