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Research Article
Bronchodilator effects of clemastine, ipratropium, bromide, and salbutamol in preschool children with asthma.
  1. R C Groggins,
  2. A D Milner,
  3. G M Stokes

    Abstract

    The bronchodilator activity in nebulised salbutamol, ipratropium bromide, clemastine, and a placebo was studied in 14 asthmatic children aged between 3 and 5 years. Changes in lung function were monitored by measuring peak expiratory flow rate and total respiratory resistance using a modification of the forced oscillation technique. Ipratropium bromide produced a degree of bronchodilation similar to that of salbutamol, but the bronchodilatory activity of clemastine was not appreciably better than for the placebo.

    https://doi.org/10.1136/adc.56.5.342

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