1α, 25-Dihydroxyvitamin D3, and 24,25-dihydroxyvitamin D3in vitro synthesis by human decidua and placenta

Y Weisman, A Harell, S Edelstein, M David, Z Spirer… - Nature, 1979 - nature.com
The biologically active metabolite of vitamin D, 1 α, 25-dihydroxyvitamin D (1 α, 25 (OH) 2D),
is synthesised by successive hydroxylation of vitamin D in the liver and kidney1. The latter …

Low-dose adrenocorticotropin test reveals impaired adrenal function in patients taking inhaled corticosteroids

…, A Golander, G Dickstein, Z Spirer… - The Journal of …, 1995 - academic.oup.com
The aim of the present study was to examine the use of low-dose ACTH-(1-24) stimulation
for assessment of adrenal function and the detection of mild adrenal insufficiency. The …

Increased apoptosis in patients with major depression: a preliminary study

…, S Mendlovic, A Doron, V Zakuth, Z Spirer - The Journal of …, 1999 - journals.aai.org
Apoptosis is a programmed cell death that can be observed in normal cells. Major
depression poses a combination of a depressed and destructive autoimmune reaction. We …

Tuftsin (an Ig-associated tetrapeptide) triggers the immunogenic function of macrophages: implications for activation of programmed cells.

…, Y Stabinsky, M Fridkin, Z Spirer… - Proceedings of the …, 1978 - National Acad Sciences
The immunoglobulin heavy-chain-associated tetrapeptide, tuftsin (Thr-Lys-Pro-Arg), known
for its phagocytosis-stimulating activity, was found to augment the antigen-specific …

Post‐splenectomy antibiotic prophylaxis—unfinished story: to treat or not to treat?

C Kaplinsky, Z Spirer - Pediatric blood & cancer, 2006 - Wiley Online Library
Overwhelming infection in asplenic patients is a well documented occurrence in the
literature. The introduction of immunization with polyvalent pneumococcal, Hemophilus …

Effect of endothelin-1 on α-smooth muscle actin expression and on alveolar fibroblasts proliferation in interstitial lung diseases

…, Y Schwarz, S Kivity, S Ben-Efraim, Z Spirer - International journal of …, 1999 - Elsevier
Endothelin-1 (ET-1) is a potent constrictor and mitogen peptide which is expressed in
several pulmonary diseases. To elucidate the involvement of ET-1 in lung interstitial …

Vitamin D defiency and insufficiency in Orthodox and non-Ortodox Jewish mothers in Israel

…, Z Eisenberg, J Lanman, I Shapira, Z Spirer… - Israel Medical …, 2001 - ima.org.il
Background: The modest clothing that Orthodox Jewish women wear exposes very little of
their skin to sunlight. Under these conditions they may develop vitamin D deficiency, even in …

Immune activation in non-treated suicidal major depression

…, E Eilat, A Doron, J Lereya, V Zakuth, Z Spirer - Immunology letters, 1999 - Elsevier
In the following study we have analyzed cytokine secretion of T-cells of suicidal and non-
suicidal depressed patients and healthy controls. It was found that T-cells of suicidal …

Does 1, 25-dihydroxyvitamin D participate in the regulation of hormone release from endocrine glands?

…, P Vardi, S Oren, A Gougoux, Z Spirer… - The Journal of …, 1985 - academic.oup.com
The presence of receptors for 1, 25-dihydroxyvitamin D3 in the pituitary, pancreas, testis,
and ovary has raised the question of a possible direct role for 1, 25-dihydroxyvitamin D (1 …

Effect of IL-6 on alveolar fibroblast proliferation in interstitial lung diseases

…, E Fireman, M Topilsky, J Grief, S Kivity, Z Spirer… - Clinical immunology and …, 1996 - Elsevier
Alveolar macrophage–fibroblast interaction may be involved in the pathogenesis of
interstitial lung diseases (ILD). Herein, we compared IL-6 secretion from alveolar …