Submicron emulsions and their applications in oral delivery

V Mundada, M Patel, K Sawant - Critical Reviews™ in …, 2016 - dl.begellhouse.com
ABSTRACT A" submicron emulsion" is an isotropic mixture of drug, lipids, and surfactants,
usually with hydrophilic cosolvents and with droplet diameters ranging from 10 to 500 nm …

Non-thermal ultrasonic contact drying of pea protein isolate suspensions: Effects on physicochemical and functional properties

R Kapoor, G Karabulut, V Mundada, H Feng - International Journal of …, 2023 - Elsevier
Pea protein isolate (PPI) is a popular plant-based ingredient, typically produced through
alkaline-isoelectric precipitation and thermal drying. However, high temperatures and long …

Fabrication of solid lipid nanoparticles of lurasidone HCl for oral delivery: optimization, in vitro characterization, cell line studies and in vivo efficacy in schizophrenia

MH Patel, VP Mundada, KK Sawant - Drug development and …, 2019 - Taylor & Francis
Objective: The aim of the present investigation was to investigate the efficacy of solid lipid
nanoparticles (SLNs) to enhance the absorption and bioavailability of lurasidone …

Enhanced intestinal absorption of asenapine maleate by fabricating solid lipid nanoparticles using TPGS: elucidation of transport mechanism, permeability across …

M Patel, V Mundada, K Sawant - Artificial cells, nanomedicine, and …, 2019 - Taylor & Francis
The aim of the present investigation was to fabricate and evaluate solid lipid nanoparticles
(SLNs) of asenapine maleate (AM) to improve its oral bioavailability (BA). AM-SLNs were …

Heterozygous truncation mutations of the SMC1A gene cause a severe early onset epilepsy with cluster seizures in females: Detailed phenotyping of 10 new cases

…, MM Lees, A McLellan, T Montgomery, V Mundada… - …, 2017 - Wiley Online Library
Objective The phenotype of seizure clustering with febrile illnesses in infancy/early
childhood is well recognized. To date the only genetic epilepsy consistently associated with …

Optimization of milling operations using artificial neural networks (ANN) and simulated annealing algorithm (SAA)

V Mundada, SKR Narala - Materials today: proceedings, 2018 - Elsevier
Process modelling and optimization are among the two important main issues in
manufacturing. Optimization of process parameters not only increases the efficacy for …

Novel Drug Delivery Approach via Self-Microemulsifying Drug Delivery System for Enhancing Oral Bioavailability of Asenapine Maleate: Optimization, Characterization, Cell …

MH Patel, VP Mundada, KK Sawant - AAPS pharmscitech, 2019 - Springer
Asenapine maleate (AM)-loaded self-microemulsifying drug delivery system (AM-SMEDDS)
was prepared to increase its oral bioavailability. AM-SMEDDS was developed using Capryol …

Chronic iron administration increases vascular oxidative stress and accelerates arterial thrombosis

SM Day, D Duquaine, LV Mundada, RG Menon… - Circulation, 2003 - Am Heart Assoc
Background—Iron overload has been implicated in the pathogenesis of ischemic
cardiovascular events. However, the effects of iron excess on vascular function and the …

Enhanced bioavailability and antihypertensive activity of nisoldipine loaded nanoemulsion: optimization, cytotoxicity and uptake across Caco-2 cell line …

VP Mundada, MH Patel, PK Mundada… - Drug development and …, 2020 - Taylor & Francis
Objective: The present study explored the antihypertensive activity of nisoldipine in oil in
water nanoemulsion to improve its oral bioavailability via intestinal lymphatic uptake …

[PDF][PDF] Rigid molecule docking: FPGA reconfiguration for alternative force laws

T VanCourt, Y Gu, V Mundada, M Herbordt - EURASIP Journal on …, 2006 - Springer
Molecular docking is one of the primary computational methods used by pharmaceutical
companies to try to reduce the cost of drug discovery. A common docking technique, used …