DNA repair as a shared hallmark in cancer and ageing
TL Clarke, R Mostoslavsky - Molecular oncology, 2022 - Wiley Online Library
Increasing evidence demonstrates that DNA damage and genome instability play a crucial
role in ageing. Mammalian cells have developed a wide range of complex and well …
role in ageing. Mammalian cells have developed a wide range of complex and well …
Associations between maternal attention-deficit/hyperactivity disorder symptoms and parenting
A Chronis-Tuscano, VL Raggi, TL Clarke… - Journal of abnormal …, 2008 - Springer
Mothers of children with attention-deficit/hyperactivity disorder (ADHD) are at increased risk
for an ADHD diagnosis themselves, which is likely associated with impairments in parenting …
for an ADHD diagnosis themselves, which is likely associated with impairments in parenting …
The relation between maternal ADHD symptoms & improvement in child behavior following brief behavioral parent training is mediated by change in negative …
A Chronis-Tuscano, KA O'Brien, C Johnston… - Journal of abnormal …, 2011 - Springer
This study examined the extent to which maternal attention-deficit/hyperactivity disorder
(ADHD) symptoms predict improvement in child behavior following brief behavioral parent …
(ADHD) symptoms predict improvement in child behavior following brief behavioral parent …
[PDF][PDF] PRMT5 is a critical regulator of breast cancer stem cell function via histone methylation and FOXP1 expression
K Chiang, AE Zielinska, AM Shaaban… - Cell reports, 2017 - cell.com
Breast cancer progression, treatment resistance, and relapse are thought to originate from a
small population of tumor cells, breast cancer stem cells (BCSCs). Identification of factors …
small population of tumor cells, breast cancer stem cells (BCSCs). Identification of factors …
[PDF][PDF] PRMT5-dependent methylation of the TIP60 coactivator RUVBL1 is a key regulator of homologous recombination
TL Clarke, MP Sanchez-Bailon, K Chiang, JJ Reynolds… - Molecular cell, 2017 - cell.com
Protein post-translation modification plays an important role in regulating DNA repair;
however, the role of arginine methylation in this process is poorly understood. Here we …
however, the role of arginine methylation in this process is poorly understood. Here we …
Development and preliminary evaluation of an integrated treatment targeting parenting and depressive symptoms in mothers of children with attention-deficit …
A Chronis-Tuscano, TL Clarke, KA O'Brien… - Journal of consulting …, 2013 - psycnet.apa.org
Objective: More than 50% of mothers of children with attention-deficit/hyperactivity disorder
(ADHD) have a lifetime history of major depressive disorder (MDD). Maternal depressive …
(ADHD) have a lifetime history of major depressive disorder (MDD). Maternal depressive …
Rapid infusion of sodium bicarbonate and albumin into high-risk premature infants soon after birth: a controlled, prospective trial
RD Bland, TL Clarke, LB Harden - American journal of obstetrics and …, 1976 - Elsevier
We conducted a controlled, prospective trial to evaluate the effectiveness of rapidly infusing
sodium bicarbonate (NaHCO 3) and salt-poor albumin into high-risk, premature infants in …
sodium bicarbonate (NaHCO 3) and salt-poor albumin into high-risk, premature infants in …
[PDF][PDF] Cross-talk between lysine-modifying enzymes controls site-specific DNA amplifications
Acquired chromosomal DNA amplifications are features of many tumors. Although
overexpression and stabilization of the histone H3 lysine 9/36 (H3K9/36) tri-demethylase …
overexpression and stabilization of the histone H3 lysine 9/36 (H3K9/36) tri-demethylase …
Generalization of neural networks to the complex plane
TL Clarke - 1990 IJCNN International Joint Conference on …, 1990 - ieeexplore.ieee.org
A complex-valued generalization of neural networks is presented. The dynamics of complex
neural networks have parallels in discrete complex dynamics which give rise to the …
neural networks have parallels in discrete complex dynamics which give rise to the …
Histone Lysine Methylation Dynamics Control EGFR DNA Copy-Number Amplification
Acquired chromosomal DNA copy gains are a feature of many tumors; however, the
mechanisms that underpin oncogene amplification are poorly understood. Recent studies …
mechanisms that underpin oncogene amplification are poorly understood. Recent studies …