Background: Coronary heart disease and cerebrovascular disease are leading causes of
death in the United States. In 2002, the US Preventive Services Task Force (USPSTF) …

Background: Neural tube defects (NTDs) are among the most common birth defects in the
United States. In 1996, the US Preventive Services Task Force (USPSTF) recommended that …

The complex antioxidant network of plant and animal cells has the thiol tripeptide GSH at its
centre to buffer ROS (reactive oxygen species) and facilitate cellular redox signalling which …

The neural circuits responsible for animal behavior remain largely unknown. We summarize
new methods and present the circuitry of a large fraction of the brain of the fruit fly …

Influenza A virus, being responsible for seasonal epidemics and reoccurring pandemics,
represents a worldwide threat to public health. High mutation rates facilitate the generation …

Mammalian influenza viruses are descendants of avian strains that crossed the species
barrier and underwent further adaptation. Since 1997 in southeast Asia, H5N1 highly …

The baculovirus P35 protein functions to prevent apoptotic death of infected cells. We have
expressed P35 in the developing embryo and eye of the fly Drosophila melanogaster. P35 …

The metabolism of the dihydropyridine calcium antagonist and vasodilator nifedipine has
been reported to exhibit polymorphism among individual humans (Kleinbloesem, CH, van …

We present a rigorously validated and highly sensitive confirmatory real-time RT-PCR assay
(1A assay) that can be used in combination with the previously reported upE assay. Two …

The O-dealkylation of pentoxyresorufin (7-pentoxyphenoxazone) by rat liver microsomes
was examined. The reaction appeared highly specific for certain phenobarbital inducible …