The lack of standardized criteria for quantitative measurement of therapeutic response in
clinical trials poses a major obstacle for the development of new agents in chronic graft …

The complexity of chronic graft-versus-host disease (GVHD) and the lack of established
research methods have made it difficult to design, conduct, and analyze clinical trials …

Abstract On June 20, 2008, a meeting entitled “Translation of new cancer treatments from
canine to human cancer patients,” sponsored by the National Cancer Institute in Bethesda …

Abstract Learning Objectives After completing this course, the reader will be able to:
Describe the safe and effective use of oxaliplatin in patients with metastatic carcinoma of the …

Large prospective cohort studies are critical for identifying etiologic factors for disease, but
they require substantial long-term research investment. Such studies can be conducted as …

This report summarizes information on drugs recently approved by the Food and Drug
Administration, Office of Drug Evaluation I, Division of Oncology Drug Products. Five …

The use of Common Data Elements can facilitate cross-study comparisons, data
aggregation, and meta-analyses; simplify training and operations; improve overall efficiency; …

Transcription of major histocompatibility complex (MHC) class I genes is regulated by the
conserved MHC class I regulatory element (CRE). The CRE has two factor-binding sites …

Immunization in pregnancy provides a promising contribution to globally reducing neonatal
and under-five childhood mortality and morbidity. Thorough assessment of benefits and risks …

Osteogenic sarcoma is the most common bone tumor of childhood and typically occurs
during the adolescent growth spurt when growth hormone and insulin-like growth factor I …