Pediatric acute lymphoblastic leukemia generally carries a good prognosis, and most
children will be cured and become long-term survivors. However, a portion of children will …

Background: While communication plays an important role in medicine, it also often
represents a challenge when the topic at hand is the prognosis of a high-risk condition …

Infectious diseases are associated with a high morbidity and mortality rate among pediatric
cancer patients undergoing treatment or receiving a transplant. Neutropenia represents a …

The benefit of reporting unsolicited findings in Next Generation Sequencing (NGS) related to
cancer genes in children may have implications for family members, nevertheless, could …

Characterization of mitochondrial respiration in peripheral blood cells has recently emerged
as a potential biomarker for the assessment of the severity of hematological malignancies …

Agents of platinum-based chemotherapy, such as cisplatin or carboplatin, are used in the
treatment of a wide range of malignancies that affect children, such as brain tumors …

Here we show that surface-enhanced Raman scattering (SERS) analysis captures the
relative hypomethylation of DNA from patients with acute leukemia associated with Down …

Ki-67 parameter is a proliferation marker in malignant tumors. The increased proliferation
activity and the decreased prognosis in lung cancer determined us to investigate different …

Background: Shortage of replacement therapy in haemophilia is responsible for the
devastating consequences of uncontrolled bleeds, with unfavourable impact on the quality …

Pathogenic variants in BRCA1 gene in heterozygous state are known to be associated with
breast-ovarian cancer susceptibility; however, biallelic variants cause a phenotype …