[HTML][HTML] A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a …

R Harwood, B Allin, CE Jones, E Whittaker… - The Lancet Child & …, 2021 - thelancet.com
Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-
TS) is a novel condition that was first reported in April, 2020. We aimed to develop a national …

[HTML][HTML] Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2021 - thelancet.com
Background In this study, we aimed to evaluate the effects of tocilizumab in adult patients
admitted to hospital with COVID-19 with both hypoxia and systemic inflammation. Methods …

Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study

RG Khemani, L Smith, YM Lopez-Fernandez… - The Lancet …, 2019 - thelancet.com
Background Paediatric acute respiratory distress syndrome (PARDS) is associated with high
mortality in children, but until recently no paediatric-specific diagnostic criteria existed. The …

[HTML][HTML] Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2021 - thelancet.com
Background Many patients with COVID-19 have been treated with plasma containing anti-
SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent …

[HTML][HTML] Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

O Abani, A Abbas, F Abbas, J Abbas, K Abbas… - The Lancet, 2022 - thelancet.com
Background We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1–2 inhibitor,
for the treatment of patients admitted to hospital with COVID-19. Methods This randomised …

[HTML][HTML] Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2022 - thelancet.com
Background Casirivimab and imdevimab are non-competing monoclonal antibodies that
bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike …

[HTML][HTML] Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

E Abaleke, M Abbas, S Abbasi, A Abbott, A Abdelaziz… - The Lancet, 2021 - thelancet.com
Background Azithromycin has been proposed as a treatment for COVID-19 on the basis of
its immunomodulatory actions. We aimed to evaluate the safety and efficacy of azithromycin …

[HTML][HTML] Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life …

NP Boeddha, LJ Schlapbach, GJ Driessen, JA Herberg… - Critical care, 2018 - Springer
Background Sepsis is one of the main reasons for non-elective admission to pediatric
intensive care units (PICUs), but little is known about determinants influencing outcome. We …

[HTML][HTML] Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2022 - thelancet.com
Background Aspirin has been proposed as a treatment for COVID-19 on the basis of its anti-
thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients …

Comparison of intracranial pressure measurements before and after hypertonic saline or mannitol treatment in children with severe traumatic brain injury

PM Kochanek, PD Adelson, BL Rosario… - JAMA Network …, 2022 - jamanetwork.com
Importance Hyperosmolar agents are cornerstone therapies for pediatric severe traumatic
brain injury. Guideline recommendations for 3% hypertonic saline (HTS) are based on …