User profiles for "author:P M Fisher"
Patrick M. FisherCenter for Integrated Molecular Brain Imaging Verified email at nru.dk Cited by 5052 |
Altered striatal activation predicting real-world positive affect in adolescent major depressive disorder
Objective: Alterations in reward-related brain function and phenomenological aspects of
positive affect are increasingly examined in the development of major depressive disorder …
positive affect are increasingly examined in the development of major depressive disorder …
A high-resolution in vivo atlas of the human brain's serotonin system
The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels
MK Madsen, PM Fisher, D Burmester… - …, 2019 - nature.com
The main psychedelic component of magic mushrooms is psilocybin, which shows promise
as a treatment for depression and other mental disorders. Psychedelic effects are believed …
as a treatment for depression and other mental disorders. Psychedelic effects are believed …
Cortical surface-based analysis reduces bias and variance in kinetic modeling of brain PET data
Exploratory (ie, voxelwise) spatial methods are commonly used in neuroimaging to identify
areas that show an effect when a region-of-interest (ROI) analysis cannot be performed …
areas that show an effect when a region-of-interest (ROI) analysis cannot be performed …
FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity
Individual variation in physiological responsiveness to stress mediates risk for mental illness
and is influenced by both experiential and genetic factors. Common polymorphisms in the …
and is influenced by both experiential and genetic factors. Common polymorphisms in the …
Effects of HTR1A C (− 1019) G on amygdala reactivity and trait anxiety
Context Serotonin 1A (5-hydroxytryptamine 1A [5-HT 1A]) autoreceptors mediate negative
feedback inhibition of serotonergic neurons and play a critical role in regulating serotonin …
feedback inhibition of serotonergic neurons and play a critical role in regulating serotonin …
[HTML][HTML] Acute 5-HT reuptake blockade potentiates human amygdala reactivity
Abstract Variability in serotonin (5-HT) function is associated with individual differences in
normal mood and temperament, as well as psychiatric illnesses, all of which are influenced …
normal mood and temperament, as well as psychiatric illnesses, all of which are influenced …
[HTML][HTML] Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience
MK Madsen, DS Stenbæk, A Arvidsson… - European …, 2021 - Elsevier
The emerging novel therapeutic psilocybin produces psychedelic effects via engagement of
cerebral serotonergic targets by psilocin (active metabolite). The serotonin 2A receptor …
cerebral serotonergic targets by psilocin (active metabolite). The serotonin 2A receptor …
Medial Prefrontal Cortex 5-HT2A Density Is Correlated with Amygdala Reactivity, Response Habituation, and Functional Coupling
PM Fisher, CC Meltzer, JC Price, RL Coleman… - Cerebral …, 2009 - academic.oup.com
Feedback inhibition of the amygdala via medial prefrontal cortex (mPFC) is an important
component in the regulation of complex emotional behaviors. The functional dynamics of …
component in the regulation of complex emotional behaviors. The functional dynamics of …
Interaction between trait anxiety and trait anger predict amygdala reactivity to angry facial expressions in men but not women
The amygdala is critically involved in mediating physiological and behavioral responses to
threat. In particular, neuroimaging research indicates that the amygdala is highly responsive …
threat. In particular, neuroimaging research indicates that the amygdala is highly responsive …