HDAC3: taking the SMRT-N-CoRrect road to repression

P Karagianni, J Wong - Oncogene, 2007 - nature.com
Known histone deacetylases (HDACs) are divided into different classes, and HDAC3
belongs to Class I. Through forming multiprotein complexes with the corepressors SMRT …

[PDF][PDF] Single-cell analysis of human mononuclear phagocytes reveals subset-defining markers and identifies circulating inflammatory dendritic cells

…, J Chen, A Larbi, HKK Tan, TKH Lim, P Karagianni… - Immunity, 2019 - cell.com
Human mononuclear phagocytes comprise phenotypically and functionally overlapping
subsets of dendritic cells (DCs) and monocytes, but the extent of their heterogeneity and …

Epigenetic perspectives on systemic autoimmune disease

P Karagianni, AG Tzioufas - Journal of Autoimmunity, 2019 - Elsevier
Autoimmune diseases are characterized by increased reactivity of the immune system
towards self-antigens, causing tissue damage. Although their etiology remains largely …

Transcription factor networks regulating hepatic fatty acid metabolism

P Karagianni, I Talianidis - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Tight regulation of lipid levels is critical for cellular and organismal homeostasis, not only in
terms of energy utilization and storage, but also to prevent potential toxicity. The liver utilizes …

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation

P Karagianni, L Amazit, J Qin… - Molecular and cellular …, 2008 - Taylor & Francis
Methylation of histone H3 on lysine 9 is critical for diverse biological processes including
transcriptional repression, heterochromatin formation, and X inactivation. The biological …

[HTML][HTML] Cooperativity and rapid evolution of cobound transcription factors in closely related mammals

…, MD Wilson, I Streeter, J Aleksic, P Karagianni… - Cell, 2013 - cell.com
To mechanistically characterize the microevolutionary processes active in altering
transcription factor (TF) binding among closely related mammals, we compared the genome …

[HTML][HTML] LSD1 promotes oxidative metabolism of white adipose tissue

D Duteil, E Metzger, D Willmann, P Karagianni… - Nature …, 2014 - nature.com
Exposure to environmental cues such as cold or nutritional imbalance requires white
adipose tissue (WAT) to adapt its metabolism to ensure survival. Metabolic plasticity is …

High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA–tRNA interface

BM Schmitt, KLM Rudolph, P Karagianni… - Genome …, 2014 - genome.cshlp.org
The genetic code is an abstraction of how mRNA codons and tRNA anticodons molecularly
interact during protein synthesis; the stability and regulation of this interaction remains …

Kinetic and mechanistic study of photocatalytic degradation of flame retardant Tris (1-chloro-2-propyl) phosphate (TCPP)

M Antonopoulou, P Karagianni… - Applied Catalysis B …, 2016 - Elsevier
In the present work, a comprehensive study on the application of TiO 2 photocatalysis for the
removal of the flame retardant tris (1-chloro-2-propyl) phosphate (TCPP) from both ultrapure …

Early versus delayed minimal enteral feeding and risk for necrotizing enterocolitis in preterm growth-restricted infants with abnormal antenatal Doppler results

P Karagianni, DD Briana, G Mitsiakos… - American journal of …, 2009 - thieme-connect.com
We studied the effect of early (≤ 5 days) versus delayed (≥ 6 days) initiation of minimal
enteral feeding (MEF) on the incidence of necrotizing enterocolitis (NEC) and feeding …