Prevalence and Diversity of Constitutional Mutations in the p53 Gene among 21 Li-Fraumeni Families

JM Birch, AL Hartley, KJ Tricker, J Prosser, A Condie… - Cancer research, 1994 - AACR
The entire coding sequence of the p53 gene was analysed for the presence of mutations in
12 families conforming to a restricted definition of Li-Fraumeni syndrome (classic LFS) and …

Ovarian failure following abdominal irradiation in childhood: the radiosensitivity of the human oocyte

WHB Wallace, SM Shalet, JH Hendry… - The British journal of …, 1989 - academic.oup.com
Ovarian function has been studied sequentially since 1975 in 19 patients treated in
childhood for an intra-abdominal tumour with surgery and whole abdominal radiotherapy …

Ovarian failure following abdominal irradiation in childhood: natural history and prognosis

WHB Wallace, SM Shalet, EC Crowne… - Clinical oncology, 1989 - Elsevier
Ovarian function has been reviewed sequentially since 1975 in 53 patients treated in
childhood between 1942 and 1985 for an intra-abdominal tumour with surgery and external …

Gonadal dysfunction due to cis‐platinum

WHB Wallace, SM Shalet, EC Crowne… - Medical and …, 1989 - Wiley Online Library
Gonadal function was studied in 15 patients, 12 pubertal or postpubertal, and three
prepubertal, who had been treated during childhood for nonmetastatic osteosarcoma of the …

Male fertility in long‐term survivors of childhood acute lymphoblastic leukaemia

WHB Wallace, SM Shalet, M Lendon… - … journal of andrology, 1991 - Wiley Online Library
To study long‐term testicular function following the treatment of acute lymphoblastic
leukaemia (ALL) in childhood, 37 young adult males were assessed at two separate time …

Ovarian function following the treatment of childhood acute lymphoblastic leukaemia

WHB Wallace, SM Shalet, LJ Tetlow… - Medical and …, 1993 - Wiley Online Library
Ovarian function was assessed in 40 long term survivors who had received standard United
Kingdom Acute Lymphoblastic Leukaemia (UKALL) protocols and were in first clinical and …

Growth in children treated for acute lymphoblastic leukaemia

PE Clayton, PH Morris-Jones, SM Shalet, DA Price - The Lancet, 1988 - Elsevier
Growth was assessed in 82 children with acute lymphoblastic leukaemia (ALL) who
achieved complete continuous first remission following treatment. 34 received prophylactic …

Prognosis of the neurological complications of acute hypernatraemia

PH Morris-Jones, IB Houston, RC Evans - The Lancet, 1967 - Elsevier
of a series of 50 cases of acute hypernatræmia had a neurological syndrome which included
convulsions, muscular hypertonicity, and depression of consciousness. This syndrome was …

Pituitary function after treatment of intracranial tumours in children

SM Shalet, PH Morris-Jones, CG Beardwell, D Pearson - The Lancet, 1975 - Elsevier
Pituitary-function tests have been done in twenty-seven patients at various times after
treatment in childhood for intracranial tumours not directly involving the …

Leydig cell damage after testicular irradiation for lymphoblastic leukaemia

SM Shalet, A Horner, SR Ahmed… - Medical and pediatric …, 1985 - Wiley Online Library
The effect of testicular irradiation on Leydig cell function has been studied in a group of boys
irradiated between 1 and 5 years earlier for a testicular relapse of acute lymphoblastic …