Macular pigments: their characteristics and putative role

NP Davies, AB Morland - Progress in Retinal and Eye Research, 2004 - Elsevier
The macular pigments (MP) absorb light in the blue–green region of the visible spectrum
and comprise two carotenoids, lutein and zeaxanthin. In humans the concentration of MP …

Multi‐centre reproducibility of diffusion MRI parameters for clinical sequences in the brain

M Grech‐Sollars, PW Hales, K Miyazaki… - NMR in …, 2015 - Wiley Online Library
The purpose of this work was to assess the reproducibility of diffusion imaging, and in
particular the apparent diffusion coefficient (ADC), intra‐voxel incoherent motion (IVIM) …

[HTML][HTML] Multiparametric magnetic resonance imaging for quantitation of liver disease: a two-centre cross-sectional observational study

N McDonald, PJ Eddowes, J Hodson, SIK Semple… - Scientific reports, 2018 - nature.com
Liver MultiScan is an emerging diagnostic tool using multiparametric MRI to quantify liver
disease. In a two-centre prospective validation study, 161 consecutive adult patients who …

Texture analysis of T1‐ and T2‐weighted MR images and use of probabilistic neural network to discriminate posterior fossa tumours in children

E Orphanidou‐Vlachou, N Vlachos… - NMR in …, 2014 - Wiley Online Library
Brain tumours are the most common solid tumours in children, representing 20% of all
cancers. The most frequent posterior fossa tumours are medulloblastomas, pilocytic …

Dual-5α-reductase inhibition promotes hepatic lipid accumulation in man

JM Hazlehurst, AI Oprescu, N Nikolaou… - The Journal of …, 2016 - academic.oup.com
Abstract Context: 5α-Reductase 1 and 2 (SRD5A1, SRD5A2) inactivate cortisol to 5α-
dihydrocortisol in addition to their role in the generation of DHT. Dutasteride (dual SRD5A1 …

Exposure of primary orbital implants in postenucleation retinoblastoma patients

V Lee, I Subak-Sharpe, JL Hungerford, NP Davies… - Ophthalmology, 2000 - Elsevier
PURPOSE: To determine significant factors influencing the exposure of primary orbital
implants in patients with retinoblastoma. DESIGN: Retrospective noncomparative case …

Selective arterial spin labeling (SASL): perfusion territory mapping of selected feeding arteries tagged using two‐dimensional radiofrequency pulses

NP Davies, P Jezzard - … in Medicine: An Official Journal of the …, 2003 - Wiley Online Library
To date, most perfusion magnetic resonance imaging (MRI) methods using arterial spin
labeling (ASL) have employed slab‐selective inversion pulses or continuous labeling within …

Application of pattern recognition techniques for classification of pediatric brain tumors by in vivo 3T 1H‐MR spectroscopy—A multi‐center study

N Zarinabad, LJ Abernethy, S Avula… - Magnetic …, 2018 - Wiley Online Library
Purpose 3T magnetic resonance scanners have boosted clinical application of 1H‐MR
spectroscopy (MRS) by offering an improved signal‐to‐noise ratio and increased spectral …

[HTML][HTML] High resolution magic angle spinning 1H NMR of childhood brain and nervous system tumours

M Wilson, NP Davies, MA Brundler, C McConville… - Molecular Cancer, 2009 - Springer
Background Brain and nervous system tumours are the most common solid cancers in
children. Molecular characterisation of these tumours is important for providing novel …

[HTML][HTML] MR spectroscopy-based brain metabolite profiling in propionic acidaemia: metabolic changes in the basal ganglia during acute decompensation and effect of …

JE Davison, NP Davies, M Wilson, Y Sun… - Orphanet journal of rare …, 2011 - Springer
Background Propionic acidaemia (PA) results from deficiency of Propionyl CoA carboxylase,
the commonest form presenting in the neonatal period. Despite best current management …