Pharmacological treatment of children with gastro‐oesophageal reflux
Background Gastro‐oesophageal reflux (GOR) is a common disorder, characterised by
regurgitation of gastric contents into the oesophagus. GOR is a very common presentation in …
regurgitation of gastric contents into the oesophagus. GOR is a very common presentation in …
Surgical management of Crohn disease in children: guidelines from the Paediatric IBD Porto Group of ESPGHAN
J Amil-Dias, S Kolacek, D Turner… - Journal of pediatric …, 2017 - journals.lww.com
The incidence of Crohn disease (CD) has been increasing and surgery needs to be
contemplated in a substantial number of cases. The relevant advent of biological treatment …
contemplated in a substantial number of cases. The relevant advent of biological treatment …
[HTML][HTML] Constipation in children
NA Afzal, MP Tighe, MA Thomson - Italian Journal of Pediatrics, 2011 - Springer
Constipation remains a frequent presentation to paediatricians, with significant health
resource implications. We present a practical guide to the management of paediatric …
resource implications. We present a practical guide to the management of paediatric …
Colonic Crohn's disease in children does not respond well to treatment with enteral nutrition if the ileum is not involved
NA Afzal, S Davies, M Paintin… - Digestive diseases and …, 2005 - Springer
Data supporting a response to treatment with exclusive enteral nutrition in pediatric colonic
Crohn's disease are few. We examined clinical and biochemical responses of ileal, colonic …
Crohn's disease are few. We examined clinical and biochemical responses of ileal, colonic …
Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes
Background Multiple genes have been implicated by association studies in altering
inflammatory bowel disease (IBD) predisposition. Paediatric patients often manifest more …
inflammatory bowel disease (IBD) predisposition. Paediatric patients often manifest more …
Current pharmacological management of gastro-esophageal reflux in children: an evidence-based systematic review
MP Tighe, NA Afzal, A Bevan, RM Beattie - Pediatric Drugs, 2009 - Springer
Gastro-esophageal reflux (GER) is a common phenomenon, characterized by the
regurgitation of the gastric contents into the esophagus. Gastro-esophageal reflux disease …
regurgitation of the gastric contents into the esophagus. Gastro-esophageal reflux disease …
Body composition in childhood inflammatory bowel disease
AE Wiskin, SA Wootton, TM Hunt, VR Cornelius… - Clinical nutrition, 2011 - Elsevier
BACKGROUND & AIMS: Little is known about the impact of disease and treatment on the
pattern of growth in children with Inflammatory Bowel Disease (IBD). Significant deficits in …
pattern of growth in children with Inflammatory Bowel Disease (IBD). Significant deficits in …
Increased prevalence of anti‐TNF therapy in paediatric inflammatory bowel disease is associated with a decline in surgical resections during childhood
JJ Ashton, F Borca, E Mossotto… - Alimentary …, 2019 - Wiley Online Library
Background Anti‐tumour necrosis factor‐α (anti‐TNF) therapy use has risen in paediatric‐
onset inflammatory bowel disease (PIBD). Whether this has translated into …
onset inflammatory bowel disease (PIBD). Whether this has translated into …
Use of biosimilars in pediatric inflammatory bowel disease: an updated position statement of the Pediatric IBD Porto Group of ESPGHAN
Biologic therapies have changed the outcome of both adult and pediatric patients with
Inflammatory Bowel Disease (IBD). In September 2013, the first biosimilar of infliximab was …
Inflammatory Bowel Disease (IBD). In September 2013, the first biosimilar of infliximab was …
Is the incidence of paediatric inflammatory bowel disease still increasing?
There has been an increase in the incidence of paediatric inflammatory bowel disease
(PIBD) over the last 20 years. 1 2 We have previously published data from Wessex, England …
(PIBD) over the last 20 years. 1 2 We have previously published data from Wessex, England …