The ability of high-dose intravenous gammaglobulin (IVGG) to prevent the coronary artery
lesion of Kawasaki disease has been studied in a multicentre controlled trial of IVGG plus …

Abstract Diagnostic guidelines for Kawasaki Disease was revised to meet the present
situation in 2002. This issue intends to explain new guidelines and their backgrounds. Major …

Background: The aim of the present study was to determine the prevalence of coronary
artery abnormality (CAA) and other clinical features in patients with incomplete Kawasaki …

For assessing carcinogenicity in animals, it is difficult and costly, an alternative strategy has
been desired. We explored the possibility of applying a toxicogenomics approach by using …

Emerging evidence demonstrates functional contributions of microRNAs (miRNAs) to μ-
opioid receptor (MOR) signaling, but the information so far has been mostly limited to their …

To examine morphological and gene expression changes induced by T-2 toxin in the fetal
brain in detail, pregnant rats on day 13 of gestation were treated orally with a single dose of …

Pregnant rats on day 13 of gestation were treated orally with 2mg/kg of T-2 toxin and
sacrificed at 1, 3, 6, 9 and 12h after the treatment (HAT). Histopathologically, the number of …

Toxicogenomics (TGx) is a widely used technique in the preclinical stage of drug
development to investigate the molecular mechanisms of toxicity. A number of candidate …

Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to
cause adverse effects to human and other mammals. Organs with high metabolism and …

Background The skeletal muscle index (SMI), which is calculated as the ratio of skeletal
muscle area at the third lumbar vertebral level divided by height squared, has been …