Pharmacological treatment of children with gastro‐oesophageal reflux

M Tighe, NA Afzal, A Bevan, A Hayen… - Cochrane Database …, 2014 - cochranelibrary.com
Background Gastro‐oesophageal reflux (GOR) is a common disorder, characterised by
regurgitation of gastric contents into the oesophagus. GOR is a very common presentation in …

Refeeding syndrome with enteral nutrition in children: a case report, literature review and clinical guidelines

NA Afzal, S Addai, A Fagbemi, S Murch, M Thomson… - Clinical nutrition, 2002 - Elsevier
Refeeding syndrome is a potentially fatal complication of the nutritional management of
severely malnourished patients. The syndrome almost always develops during the early …

Surgical management of Crohn disease in children: guidelines from the Paediatric IBD Porto Group of ESPGHAN

J Amil-Dias, S Kolacek, D Turner… - Journal of pediatric …, 2017 - journals.lww.com
The incidence of Crohn disease (CD) has been increasing and surgery needs to be
contemplated in a substantial number of cases. The relevant advent of biological treatment …

Colonic Crohn's disease in children does not respond well to treatment with enteral nutrition if the ileum is not involved

NA Afzal, S Davies, M Paintin… - Digestive diseases and …, 2005 - Springer
Data supporting a response to treatment with exclusive enteral nutrition in pediatric colonic
Crohn's disease are few. We examined clinical and biochemical responses of ileal, colonic …

Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes

K Christodoulou, AE Wiskin, J Gibson, W Tapper… - Gut, 2013 - gut.bmj.com
Background Multiple genes have been implicated by association studies in altering
inflammatory bowel disease (IBD) predisposition. Paediatric patients often manifest more …

A British Society of Paediatric Gastroenterology, Hepatology and Nutrition survey of the effectiveness and safety of adalimumab in children with inflammatory bowel …

RK Russell, ML Wilson, S Loganathan… - Alimentary …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 33: 946–953 Summary Background Adalimumab is
efficacious therapy for adults with Crohn's disease (CD). Aim To summarise the United …

Diagnostic role of upper gastrointestinal endoscopy in pediatric inflammatory bowel disease

SP Castellaneta, NA Afzal, M Greenberg… - Journal of pediatric …, 2004 - Wiley Online Library
Background: Discrimination between ulcerative colitis (UC) and Crohn disease (CD) may be
difficult on ileo‐colonoscopy alone because of a lack of definitive lesions. Retrospective …

Improvement in quality of life of children with acute Crohn's disease does not parallel mucosal healing after treatment with exclusive enteral nutrition

NA Afzal, HJ Van der Zaag‐Loonen… - Alimentary …, 2004 - Wiley Online Library
Background: Crohn's disease is a chronic debilitating disorder affecting a child's physical
and emotional well‐being. Recent emphasis on 'quality of life'(QOL) has led to re‐evaluation …

[HTML][HTML] Constipation in children

NA Afzal, MP Tighe, MA Thomson - Italian Journal of Pediatrics, 2011 - Springer
Constipation remains a frequent presentation to paediatricians, with significant health
resource implications. We present a practical guide to the management of paediatric …

Endoscopy in pediatric inflammatory bowel disease: a position paper on behalf of the Porto IBD Group of the European Society for Pediatric Gastroenterology …

S Oliva, M Thomson, L De Ridder… - Journal of pediatric …, 2018 - journals.lww.com
Endoscopy is a central tool for the evaluation and management of inflammatory bowel
disease (IBD). In the last few decades, gastrointestinal (GI) endoscopy has undergone …