Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1. 5 blockers

S Wu, A Fluxe, J Sheffer, JM Janusz, BE Blass… - Bioorganic & medicinal …, 2006 - Elsevier
Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1.5 blockers - ScienceDirect
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Discovery and synthesis of tetrahydroindolone derived semicarbazones as selective Kv1. 5 blockers

S Wu, A Fluxe, JM Janusz, JB Sheffer… - Bioorganic & medicinal …, 2006 - Elsevier
A novel class of tetrahydroindolone-derived semicarbazones has been discovered as potent
Kv1. 5 blockers. In in vitro studies, several compounds exhibited very good potency for …

Synthesis and evaluation of (2-phenethyl-2H-1, 2, 3-triazol-4-yl)(phenyl) methanones as Kv1. 5 channel blockers for the treatment of atrial fibrillation

BE Blass, K Coburn, W Lee, N Fairweather… - Bioorganic & medicinal …, 2006 - Elsevier
Synthesis and evaluation of (2-phenethyl-2H-1,2,3-triazol-4-yl)(phenyl)methanones as Kv1.5
channel blockers for the treatment of atrial fibrillation - ScienceDirect Skip to main contentSkip …

Question 1 Chloral hydrate or midazolam: which is better for sedating children for painless diagnostic imaging?

M Hare - Archives of disease in childhood, 2012 - adc.bmj.com
Medline (1948 to March week 5 2011) and Embase (1947 to 8 April 2011) were searched
via Ovid on 11 April 2011 using the search terms ((chloral adj2 hydrate) AND midazolam) …

Discovery and synthesis of tetrahydroindolone-derived carbamates as Kv1. 5 blockers

A Fluxe, S Wu, JB Sheffer, JM Janusz… - Bioorganic & medicinal …, 2006 - Elsevier
A novel class of tetrahydroindolone-derived carbamates has been discovered whose
members are potent Kv1. 5 blockers. The in vitro data show that compounds 6 and 29 are …

Inhibition of Human Neutrophil Elastase. 4. Design, Synthesis, X-ray Crystallographic Analysis, and Structure−Activity Relationships for a Series of P2-Modified, Orally …

RJ Cregge, SL Durham, RA Farr… - Journal of medicinal …, 1998 - ACS Publications
A series of P2-modified, orally active peptidic inhibitors of human neutrophil elastase (HNE)
are reported. These pentafluoroethyl ketone-based inhibitors were designed using …

Handstands: a treatment for supraventricular tachycardia?

M Hare, S Ramlakhan - Archives of disease in childhood, 2015 - adc.bmj.com
Supraventricular tachycardia (SVT) is the most common symptomatic tachyarrhythmia in
childhood. Treatment involves vagal manoeuvres, pharmacological agents or electrical …

Inhibition of human neutrophil elastase with peptidyl electrophilic ketones. 2. Orally active PG-Val-Pro-Val pentafluoroethyl ketones

MR Angelastro, LE Baugh, P Bey… - Journal of medicinal …, 1994 - ACS Publications
Valylprolylvalyl pentafluoroethyl ketones with different N-protectinggroups were evaluated in
vitro and in vivo as inhibitors of human neutrophil elastase (HNE). Several of these …

Inhibition of human neutrophil elastase and cathepsin G by a diphenyl disulfonic acid copolymer

MJ Janusz, M Hare - International journal of immunopharmacology, 1994 - Elsevier
The sulfated polymer MDL 101,028 was found to be a potent inhibitor of both human
neutrophil elastase (HNE) and human neutrophil cathepsin G (CatG). Cleavage of synthetic …

[CITATION][C] Fourteen-month-old girl with a rapidly enlarging swelling on the chest wall.

A Benson, M Hare - Emergency Medicine Australasia: EMA, 2020 - europepmc.org
Fourteen-month-old girl with a rapidly enlarging swelling on the chest wall. - Abstract - Europe
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