User profiles for "author:M Rigby"

Michael Rigby

Emeritus Professor of Health Information Strategy
Verified email at keele.ac.uk
Cited by 4561

Three decades of global methane sources and sinks

…, I Pison, D Plummer, B Poulter, RG Prinn, M Rigby… - Nature …, 2013 - nature.com
Methane is an important greenhouse gas, responsible for about 20% of the warming
induced by long-lived greenhouse gases since pre-industrial times. By reacting with …

Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients

…, D Geehan, B Kohl, SA Nasraway, M Rigby… - Critical care …, 2012 - journals.lww.com
Objective: To evaluate the literature and identify important aspects of insulin therapy that
facilitate safe and effective infusion therapy for a defined glycemic end point. Methods:

Molecular and functional diversity of the expanding GABA‐A receptor gene family

PJ Whiting, TP Bonnert, RM McKernan… - Annals of the New …, 1999 - Wiley Online Library
Fast inhibitory neurotransmission in the mammalian CNS is mediated primarily by the
neurotransmitter γ‐aminobutyric acid (GABA), which, upon binding to its receptor, leads to …

A receptor in pituitary and hypothalamus that functions in growth hormone release

…, A Elbrecht, M Dashkevicz, R Heavens, M Rigby… - Science, 1996 - science.org
Small synthetic molecules termed growth hormone secretagogues (GHSs) act on the
pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone …

[HTML][HTML] Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-β precursor protein and amyloidogenic Aβ peptide formation

…, Y Zhu, JQ Huang, A LeBlanc, D Smith, M Rigby… - Cell, 1999 - cell.com
The amyloid-β precursor protein (APP) is directly and efficiently cleaved by caspases during
apoptosis, resulting in elevated amyloid-β (Aβ) peptide formation. The predominant site of …

Renewed growth of atmospheric methane

M Rigby, RG Prinn, PJ Fraser… - Geophysical …, 2008 - Wiley Online Library
Following almost a decade with little change in global atmospheric methane mole fraction,
we present measurements from the Advanced Global Atmospheric Gases Experiment …

Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn

…, A Wyatt, JK Webb, R O'donnell, G Mason, M Rigby… - …, 1999 - Elsevier
The present study investigated the regional distribution of the N-methyl-d-aspartate (NMDA)
receptor containing the NR2B subunit protein in rat lumbar spinal cord and examined …

[BOOK][B] Paediatric cardiology

RH Anderson, EJ Baker, A Redington, ML Rigby… - 2009 - books.google.com
As patients live longer and need to be treated over the long term and the management of
pediatric cardiology problems and congenital heart disease moves more into the …

TransCom model simulations of CH4 and related species: linking transport, surface flux and chemical loss with CH4 variability in the troposphere and lower …

…, L Meng, PI Palmer, RG Prinn, M Rigby… - Atmospheric …, 2011 - acp.copernicus.org
A chemistry-transport model (CTM) intercomparison experiment (TransCom-CH 4) has been
designed to investigate the roles of surface emissions, transport and chemical loss in …

Role of atmospheric oxidation in recent methane growth

M Rigby, SA Montzka, RG Prinn… - Proceedings of the …, 2017 - National Acad Sciences
The growth in global methane (CH4) concentration, which had been ongoing since the
industrial revolution, stalled around the year 2000 before resuming globally in 2007. We …