Purpose This study evaluated the efficacy of oropharyngeal exercises in children with
symptoms of obstructive sleep apnea syndrome (OSA) after adenotonsillectomy. Methods …

Trace amine‐associated receptor 1 (TAAR1) is a G protein–coupled receptor that belongs to
the family of TAAR receptors and responds to a class of compounds called trace amines …

Clonidine and benazoline are two structurally related imidazolines. Whereas clonidine binds
both to α2-adrenoceptors (α2R) and to I1 imidazoline receptors (I1R), benazoline showed a …

Trace Amine‐Associated Receptor 1 (TAAR 1) is a G protein‐coupled receptor that is
expressed in brain and periphery and responds to a class of compounds called trace …

Abstract Histone Deacetylases (HDACs) are among the most attractive and interesting
targets in anticancer drug discovery. The clinical relevance of HDAC inhibitors (HDACIs) is …

Abstract Recently, 1-(1, 4-dioxaspiro [4, 5] dec-2-ylmethyl)-4-(2-methoxyphenyl) piperazine
(1) was reported as a potent 5-HT 1A R agonist with a moderate 5-HT 1A R selectivity. In an …

A series of aralkylphenoxyethylamine and aralkylmethoxyphenylpiperazine compounds was
synthesized and their in vitro pharmacological profile at both 5-HT1A receptors and α1 …

Objective Neonatal asphyxia accounts for a quarter of neonatal deaths. We aimed to assess
factors associated with mortality among asphyxiated neonates in a low-resource setting …

The observation that all the attempts to characterize imidazoline (I) receptors have been
carried out with non-selective or poorly selective ligands prompted us to undertake research …

The management of advanced-stage melanoma is clinically challenging, mainly because of
its resistance to the currently available therapies. Therefore, it is important to develop …