User profiles for "author:Kun-Hsing Yu"

Kun-Hsing Yu

Harvard Medical School
Verified email at hms.harvard.edu
Cited by 6376

Artificial intelligence in healthcare

KH Yu, AL Beam, IS Kohane - Nature biomedical engineering, 2018 - nature.com
Artificial intelligence (AI) is gradually changing medical practice. With recent progress in
digitized data acquisition, machine learning and computing infrastructure, AI applications …

Examining the use of real‐world evidence in the regulatory process

BK Beaulieu‐Jones, SG Finlayson… - Clinical …, 2020 - Wiley Online Library
The 21st Century Cures Act passed by the United States Congress mandates the US Food
and Drug Administration to develop guidance to evaluate the use of real‐world evidence …

[HTML][HTML] Omics profiling in precision oncology

KH Yu, M Snyder - Molecular & Cellular Proteomics, 2016 - ASBMB
Cancer causes significant morbidity and mortality worldwide, and is the area most targeted
in precision medicine. Recent development of high-throughput methods enables detailed …

[HTML][HTML] Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features

KH Yu, C Zhang, GJ Berry, RB Altman, C Ré… - Nature …, 2016 - nature.com
Lung cancer is the most prevalent cancer worldwide, and histopathological assessment is
indispensable for its diagnosis. However, human evaluation of pathology slides cannot …

[HTML][HTML] Integrated proteogenomic characterization of human high-grade serous ovarian cancer

H Zhang, T Liu, Z Zhang, SH Payne, B Zhang… - Cell, 2016 - cell.com
To provide a detailed analysis of the molecular components and underlying mechanisms
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …

[HTML][HTML] Histopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients

PC Tsai, TH Lee, KC Kuo, FY Su, TLM Lee… - Nature …, 2023 - nature.com
Histopathologic assessment is indispensable for diagnosing colorectal cancer (CRC).
However, manual evaluation of the diseased tissues under the microscope cannot reliably …

Suicide rates among adolescents and young adults in the United States, 2000-2017

O Miron, KH Yu, R Wilf-Miron, IS Kohane - Jama, 2019 - jamanetwork.com
Methods| We searched the CDC Underlying Cause of Death database, a national data set
based on death certificates and population estimates from the US Census Bureau. This data …

Framing the challenges of artificial intelligence in medicine

KH Yu, IS Kohane - BMJ quality & safety, 2019 - qualitysafety.bmj.com
On a clear January morning in Florida, a Tesla enthusiast and network entrepreneur was
driving his new Tesla Model S on US Highway 27A, returning from a family trip. He had …

[PDF][PDF] Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro

E Matsa, PW Burridge, KH Yu, JH Ahrens… - Cell stem cell, 2016 - cell.com
Understanding individual susceptibility to drug-induced cardiotoxicity is key to improving
patient safety and preventing drug attrition. Human induced pluripotent stem cells (hiPSCs) …

Does one size fit all? Building a framework for medical professionalism

MJ Ho, KH Yu, D Hirsh, TS Huang, PC Yang - Academic Medicine, 2011 - journals.lww.com
Purpose Medical professionalism has gained global attention over the past decade, but
there is a paucity of literature on the universal applicability of the dominant professionalism …