The rates of bronchiectasis for Indigenous children from remote Australian communities are
unacceptably high, with one study showing 14.7/1000 Aboriginal children.■ Children with …

Bronchiectasis is conventionally defined as irreversible dilatation of the bronchial tree.
Bronchiectasis unrelated to cystic fibrosis is an increasingly appreciated cause of chronic …

Cough is the single most common reason for primary care physician visits and, when
chronic, a frequent indication for specialist referrals. In children, a chronic cough (> 4 weeks) …

Airway inflammation is an important component of cystic fibrosis (CF) lung disease. To
determine whether this begins early in the illness, before the onset of infection, we examined …

Objective: To determine the clinical consequences of acquiring Pseudomonas aeruginosa
infection during early childhood in children with cystic fibrosis (CF). Design: Prospective …

The nature and timing of lower respiratory infections in infants with cystic fibrosis is largely
unknown 1 because infants do not produce sputum and throat cultures may not predict lower …

The objective of this study was to assess the diagnostic accuracy of oropharyngeal (OP)
cultures relative to simultaneous bronchoalveolar lavage (BAL) cultures in very young …

AIM To determine whether intellectual and cognitive impairments observed seven years
following early childhood bacterial meningitis persist into adolescence. METHODS Blinded …

As collections of lower respiratory tract specimens from young children with cystic fibrosis
(CF) are difficult, we determined whether oropharyngeal cultures predicted lower airway …

Controversy exists over whether the lower airway inflammation that characterizes cystic
fibrosis (CF) is initiated primarily by the genetic defect. To determine if inflammation …