Brain functioning is increasingly seen as a complex interplay of dynamic neural systems that
rely on the integrity of structural and functional networks. Recent studies that have …

Background People with epilepsy who became seizure-free while taking antiepileptic drugs
might consider discontinuing their medication, with the possibility of increased quality of life …

Background Accumulating evidence suggests a role for inflammation in the pathophysiology
of epilepsy. Methods We performed a systematic review and meta-analysis of studies that …

Background Surgery is a widely accepted treatment option for drug-resistant focal epilepsy.
A detailed analysis of longitudinal postoperative seizure outcomes and use of antiepileptic …

MR offers unique tools for measuring molecular diffusion. This review focuses on the use of
diffusion‐weighted MR spectroscopy (DW‐MRS) to non‐invasively quantitate the …

Objective. To determine the genotype–phenotype association in patients with adenosine
deaminase-2 (ADA2) deficiency due to identical homozygous R169Q mutations in CECR1 …

Purpose: Diffusion tensor imaging (DTI) is used increasingly to study white matter integrity in
people with temporal lobe epilepsy (TLE). Most studies report fractional anisotropy (FA) …

Normal brain functioning is presumed to depend upon interacting regions within large-scale
neuronal networks. Increasing evidence exists that interictal network alterations in focal …

Objective Resective surgery is effective in treating drug-resistant focal epilepsy, but it
remains unclear whether improved diagnostics influence postsurgical outcomes. Here, we …

Background Postoperative antiepileptic drug (AED) withdrawal practices remain debatable
and little is known about the optimum timing. We hypothesised that early AED withdrawal …