Increased susceptibility to co-infection with enteric Gram-negative bacteria, particularly non-
typhoidal Salmonella, is reported in malaria and Oroya fever (Bartonella bacilliformis …

Bacterial conjugate vaccines have dramatically changed the epidemiology of childhood
meningitis; viral causes are increasingly predominant, but the current UK epidemiology is …

DRJA was involved in the study concept and design, analysis and interpretation of data,
review of the literature and prepared the first draft of the manuscript. FA and AS collected the …

Sickle cell disease is a risk factor for invasive bacterial infections, and splenic dysfunction is
believed to be the main underlying cause. We have previously shown that the liberation of …

Background and aims Sickle cell anaemia (SCA) is an autosomal recessive disorder caused
by point mutation of the β-globin gene, resulting in abnormal forms of hemoglobin that cause …