Age-specific evaluation of primary human papillomavirus screening vs conventional cytology in a randomized setting
M Leinonen, P Nieminen… - JNCI: Journal of the …, 2009 - academic.oup.com
Abstract Background Human papillomavirus (HPV) DNA testing has shown higher sensitivity
than cytology for detecting cervical lesions, but it is uncertain whether the higher sensitivity is …
than cytology for detecting cervical lesions, but it is uncertain whether the higher sensitivity is …
Rate of cervical cancer, severe intraepithelial neoplasia, and adenocarcinoma in situ in primary HPV DNA screening with cytology triage: randomised study within …
A Anttila, L Kotaniemi-Talonen, M Leinonen… - Bmj, 2010 - bmj.com
Objective To assess the performance and impact of primary human papillomavirus (HPV)
DNA screening with cytology triage compared with conventional cytology on cervical cancer …
DNA screening with cytology triage compared with conventional cytology on cervical cancer …
Detection rates of precancerous and cancerous cervical lesions within one screening round of primary human papillomavirus DNA testing: prospective randomised …
MK Leinonen, P Nieminen, S Lönnberg, N Malila… - Bmj, 2012 - bmj.com
Objective To compare the detection rates of precancerous and cancerous cervical lesions by
human papillomavirus (HPV) DNA testing and by conventional cytology screening. Design …
human papillomavirus (HPV) DNA testing and by conventional cytology screening. Design …
The HPV test has similar sensitivity but more overdiagnosis than the Pap test—a randomised health services study on cervical cancer screening in Finland
N Malila, M Leinonen… - … Journal of Cancer, 2013 - Wiley Online Library
We compared test sensitivity (in terms of prevented cancers) and overdiagnosis (in terms of
non‐progressive pre‐invasive lesions) between the human papillomavirus test (HPV test …
non‐progressive pre‐invasive lesions) between the human papillomavirus test (HPV test …
[HTML][HTML] Identification and validation of human papillomavirus encoded microRNAs
We report here identification and validation of the first papillomavirus encoded microRNAs
expressed in human cervical lesions and cell lines. We established small RNA libraries from …
expressed in human cervical lesions and cell lines. We established small RNA libraries from …
Adenoidectomy does not significantly reduce the incidence of otitis media in conjunction with the insertion of tympanostomy tubes in children who are younger than 4 …
S Hammaren-Malmi, H Saxen, J Tarkkanen… - Pediatrics, 2005 - publications.aap.org
Objective. To evaluate the efficacy of adenoidectomy in reducing the incidence of otitis
media among children who are younger than 4 years and receive tympanostomy tubes …
media among children who are younger than 4 years and receive tympanostomy tubes …
Causes of tonsillar disease and frequency of tonsillectomy operations
PS Mattila, O Tahkokallio, J Tarkkanen… - … –Head & Neck …, 2001 - jamanetwork.com
Objective To characterize the factors that influence the frequency of tonsillectomy and
adenoidectomy operations. Design and Setting Nationwide questionnaire. Analysis of …
adenoidectomy operations. Design and Setting Nationwide questionnaire. Analysis of …
Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma
S Saarinen, M Aavikko, K Aittomäki… - Blood, The Journal …, 2011 - ashpublications.org
A strong clustering of Hodgkin lymphoma in certain families has been long acknowledged.
However, the genetic factors in the background of familial Hodgkin lymphoma are largely …
However, the genetic factors in the background of familial Hodgkin lymphoma are largely …
Presenting symptoms and clinical findings in HPV-positive and HPV-negative oropharyngeal cancer patients
T Carpén, A Sjöblom, M Lundberg, C Haglund… - Acta oto …, 2018 - Taylor & Francis
Objectives: Oropharyngeal squamous cell carcinoma (OPSCC) is divided in two different
disease entities depending on HPV involvement. We investigated differences in presenting …
disease entities depending on HPV involvement. We investigated differences in presenting …
In situ hybridization for high-risk HPV E6/E7 mRNA is a superior method for detecting transcriptionally active HPV in oropharyngeal cancer
R Randén-Brady, T Carpén, L Jouhi, S Syrjänen… - Human Pathology, 2019 - Elsevier
Current human papillomavirus (HPV) detection methods in oropharyngeal squamous cell
carcinoma (OPSCC) have varying sensitivity and specificity. We aimed to compare different …
carcinoma (OPSCC) have varying sensitivity and specificity. We aimed to compare different …