Argonaute proteins were first discovered genetically, and extensive research in the past few
years has revealed that members of the Argonaute protein family are key players in gene …

MicroRNAs (miRNAs) have been implicated in sequence-specific cleavage, translational
repression or deadenylation of specific target mRNAs resulting in post-transcriptional gene …

Small regulatory RNAs including small interfering RNAs (siRNAs) and microRNAs (miRNAs)
guide Argonaute (Ago) proteins to specific target RNAs leading to mRNA destabilization or …

Members of the Argonaute (Ago) protein family associate with small RNAs and have
important roles in RNA silencing. Here, we analysed Ago1‐and Ago2‐containing protein …

Studies of RNA interference (RNAi) provide evidence that in addition to the well-
characterized cytoplasmic mechanisms, nuclear mechanisms also exist. The mechanism by …

Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) is a key determinant in the EBV-driven
B-cell growth transformation process. By activating an array of viral and cellular target …

Aim Health‐related quality of life (HrQoL) is a multidimensional concept including self‐
reported measures of physical and mental health. Throughout the last decades, HrQoL has …

Objective To compare daily physical activity of children with congenital heart disease (CHD)
with healthy peers measured using wearables bracelets in a large cohort. Additionally …

Objective Children and adolescents with an univentricular heart after total cavopulmonary
connection (TCPC) have functional impairments. This study assesses health-related …

Aims There has been a growing interest in the use of markers of aerobic physical fitness
(VO2max assessed by cardiopulmonary exercise test (CPET)) in the follow-up of paediatric …