The global problem of childhood diarrhoeal diseases: emerging strategies in prevention and management

M Mokomane, I Kasvosve, E Melo… - Therapeutic …, 2018 - journals.sagepub.com
Acute diarrhoeal diseases remain a leading cause of global morbidity and mortality
particularly among young children in resource-limited countries. Recent large studies …

[HTML][HTML] Identification and management of Shigella infection in children with diarrhoea: a systematic review and meta-analysis

KD Tickell, RL Brander, HE Atlas, JM Pernica… - The Lancet Global …, 2017 - thelancet.com
Background Shigella infections are a leading cause of diarrhoeal death among children in
low-income and middle-income countries. WHO guidelines reserve antibiotics for treating …

Short-course antimicrobial therapy for pediatric community-acquired pneumonia: the SAFER randomized clinical trial

JM Pernica, S Harman, AJ Kam, R Carciumaru… - JAMA …, 2021 - jamanetwork.com
Importance Community-acquired pneumonia (CAP) is a common occurrence in childhood;
consequently, evidence-based recommendations for its treatment are required. Objective To …

Bleach baths for atopic dermatitis: A systematic review and meta-analysis including unpublished data, Bayesian interpretation, and GRADE

L Bakaa, JM Pernica, RJ Couban, KJ Tackett… - Annals of Allergy …, 2022 - Elsevier
Background Bleach bathing is frequently recommended to treat atopic dermatitis (AD), but its
efficacy and safety are uncertain. Objective To systematically synthesize randomized …

Self-collected saline gargle samples as an alternative to health care worker-collected nasopharyngeal swabs for COVID-19 diagnosis in outpatients

DM Goldfarb, P Tilley, GN Al-Rawahi… - Journal of clinical …, 2021 - Am Soc Microbiol
We assessed the performance, stability, and user acceptability of swab-independent self-
collected saliva and saline mouth rinse/gargle sample types for the molecular detection of …

Nirsevimab binding-site conservation in respiratory syncytial virus fusion glycoprotein worldwide between 1956 and 2021: an analysis of observational study …

D Wilkins, AC Langedijk, RJ Lebbink… - The Lancet Infectious …, 2023 - thelancet.com
Background Nirsevimab is an extended half-life monoclonal antibody to the respiratory
syncytial virus (RSV) fusion protein that has been developed to protect infants for an entire …

Pediatric RSV-associated hospitalizations before and during the COVID-19 pandemic

M Bourdeau, NK Vadlamudi, N Bastien… - JAMA Network …, 2023 - jamanetwork.com
Importance Respiratory syncytial virus (RSV) is a leading cause of pediatric hospitalizations.
Objective To describe the epidemiology and burden of RSV-associated hospitalizations …

Effectiveness of monovalent rotavirus vaccine after programmatic implementation in Botswana: a multisite prospective case-control study

PA Gastañaduy, AP Steenhoff… - Clinical Infectious …, 2016 - academic.oup.com
Background. Botswana introduced monovalent G1P [8] rotavirus vaccine (RV1) in July 2012,
providing one of the first opportunities to assess the effectiveness of routine RV1 vaccination …

Longitudinal outcomes in the 2014 acute flaccid paralysis cluster in Canada: a nationwide study

C Yea, A Bitnun, J Robinson… - Journal of Child …, 2017 - journals.sagepub.com
We describe the presenting features and long-term outcome of an unusual cluster of
pediatric acute flaccid paralysis cases that occurred in Canada during the 2014 enterovirus …

The nasopharyngeal microbiota of children with respiratory infections in Botswana

MS Kelly, MG Surette, M Smieja… - The Pediatric …, 2017 - journals.lww.com
Background: Nearly half of child pneumonia deaths occur in sub-Saharan Africa. Microbial
communities in the nasopharynx are a reservoir for pneumonia pathogens and remain …