Glaucoma is a term describing a group of ocular disorders with multi‐factorial etiology united
by a clinically characteristic intraocular pressure‐associated optic neuropathy. It is not a …

Glaucoma is an optic neuropathy that is characterized by the progressive degeneration of
the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible …

Mitochondrial dysfunction increases reactive oxygen species (ROS) production and when
this overwhelms the cellular antioxidant defences, oxidative stress ensues. Oxidative stress …

Glaucoma is increasingly recognized as a neurodegenerative disorder, characterized by the
accelerated loss of retinal ganglion cells (RGCs) and their axons. Open angle glaucoma …

Purpose: To develop and evaluate a novel bleb grading scheme for clinical and
photographic evaluation. Method: A system for grading bleb photographs using widely …

purpose. The transformed RGC-5 retinal ganglion cell line is used widely in glaucoma
research. Increased resistance to glutamate was noted in published literature and led to the …

Studies of rodent models of Alzheimer's disease (AD) and of human tissues suggest that the
retinal changes that occur in AD, including the accumulation of amyloid beta (Aβ), may serve …

Assessment of optic disk size is an important, but often overlooked, component of the
diagnostic evaluation for glaucoma. Measured values of optic disk size vary with the …

purpose. To determine whether oxidative adduct formation or heme oxygenase-1 (HO-1)
expression are altered in retinal ganglion cell (RGC) cultures exposed to elevated …

Objectives To develop and validate a predictive model to estimate the risk of conversion
from ocular hypertension to glaucoma. Methods Predictive models for the 5-year risk of …