Although interest in clinical guidelines has never been greater, uncertainty persists about
whether they are effective. The debate has been hampered by the lack of a rigorous …

Background The erosion of the early mortality advantage of elective endovascular aneurysm
repair (EVAR) compared with open repair of abdominal aortic aneurysm remains without a …

" Clinical guidelines are proliferating on both sides of the Atlantic."'Nevertheless there is
considerable uncertainty whether this will improve clinical practice. We therefore …

OBJECTIVE--To assess the validity, reliability, and acceptability of the short form 36 (SF 36)
health survey questionnaire (a shortened version of a battery of 149 health status questions) …

Objective: We compared mindfulness-based cognitive therapy (MBCT) with both cognitive
psychological education (CPE) and treatment as usual (TAU) in preventing relapse to major …

Quality of life has been defined as “the extent to which our hopes and ambitions are
matched by experience.” To improve a patient's quality of life through medical care would be …

Objective To describe the prevalence and causes of postnatal maternal morbidity. Design
Questionnaire survey of postnatal patients. Further data extracted from SMRl returns, case …

Background: Data from randomised studies are lacking on the value of interventional
procedures in the management of atheromatous renal artery stenosis. This randomised …

Background There is controversy about the value of evidence about the effectiveness of
healthcare interventions from non-randomised study designs. Advocates for quasi …

OBJECTIVE--To develop a valid and reliable outcome measure for patients with varicose
veins. DESIGN--Postal questionnaire survey of patients with varicose veins. SETTING …