Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial
Background The results of FASTACT, a randomised, placebo-controlled, phase 2 study,
showed that intercalated chemotherapy and erlotinib significantly prolonged progression …
showed that intercalated chemotherapy and erlotinib significantly prolonged progression …
Small-molecule c-Myc inhibitor, 10058-F4, inhibits proliferation, downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human …
CP Lin, JD Liu, JM Chow, CR Liu, HE Liu - Anti-cancer drugs, 2007 - journals.lww.com
Abstract c-Myc oncogene is critical for the development of hepatocellular carcinoma. Given
the successful use of small-molecule inhibitors on cancers, targeting c-Myc with small …
the successful use of small-molecule inhibitors on cancers, targeting c-Myc with small …
Low-dose or no aspirin administration in acute-phase Kawasaki disease: a meta-analysis and systematic review
MH Chiang, HE Liu, JL Wang - Archives of Disease in Childhood, 2021 - adc.bmj.com
Objective To compare the efficacy of low-dose or no aspirin with conventional high-dose
aspirin for the initial treatment in the acute-phase of Kawasaki disease (KD). Design A meta …
aspirin for the initial treatment in the acute-phase of Kawasaki disease (KD). Design A meta …
[HTML][HTML] Associations of reactive thrombocytosis with clinical characteristics in pediatric diseases
JL Wang, LT Huang, KH Wu, HW Lin, MY Ho… - Pediatrics & …, 2011 - Elsevier
BACKGROUND: Reactive thrombocytosis (RT) in pediatric patients is common, but usually
without symptoms. The incidence of RT is different depending on age. Mostly, we reason …
without symptoms. The incidence of RT is different depending on age. Mostly, we reason …
Immune response of single dose vaccination against 2009 pandemic influenza A (H1N1) in the Taiwanese elderly
TM Kao, SM Hsieh, HC Kung, YC Lee, KC Huang… - Vaccine, 2010 - Elsevier
We conducted a multi-center, randomized and laboratory-blinded clinical trial with subgroup
analyses, involving adults aged greater than 60 years old (range 61–86 years old), to …
analyses, involving adults aged greater than 60 years old (range 61–86 years old), to …
[HTML][HTML] Human Papillomavirus Oncoproteins Confer Sensitivity to Cisplatin by Interfering with Epidermal Growth Factor Receptor Nuclear Trafficking Related to More …
JL Wang, WJ Lee, CL Fang, HL Hsu, BJ Chen, HE Liu - Cancers, 2022 - mdpi.com
Simple Summary Lung cancer is the leading cause of cancer death in the world. Identifying
prognostic factors is crucial to improve the survival time of those with lung cancer. Our …
prognostic factors is crucial to improve the survival time of those with lung cancer. Our …
Sonic hedgehog antagonists induce cell death in acute myeloid leukemia cells with the presence of lipopolysaccharides, tumor necrosis factor-α, or interferons
FL Lu, CC Yu, HH Chiu, HE Liu, SY Chen, S Lin… - Investigational new …, 2013 - Springer
Due to the development of drug resistance, the outcome for the majority of patients with
acute myeloid leukemia (acute myelogenous leukemia; AML) remains poor. To prevent drug …
acute myeloid leukemia (acute myelogenous leukemia; AML) remains poor. To prevent drug …
[HTML][HTML] Prognostic value of localization of epidermal growth factor receptor in lung adenocarcinoma
JL Wang, CL Fang, YT Tzeng, HL Hsu, SE Lin… - Journal of Biomedical …, 2018 - Springer
Background The nuclear translocation of epidermal growth factor receptor (EGFR) has been
considered to play a role in carcinogenesis. However, the relevance of differentially located …
considered to play a role in carcinogenesis. However, the relevance of differentially located …
[HTML][HTML] Establishment of a cost-effective method to detect FLT-ITD and D835 mutations in acute myeloid leukemia patients in the Taiwanese population
HE Liu, CH Ko, F Lam, LSH Wu, KF Lee - Tzu Chi Medical Journal, 2015 - Elsevier
Objective The FMS-related tyrosine kinase 3 (FLT-3) gene is a hematopoietic growth factor
receptor gene, an independent negative prognostic factor, which affects the proliferation and …
receptor gene, an independent negative prognostic factor, which affects the proliferation and …
Efficacy and toxicity of HLX07 as a new anti-EGFR monoclonal antibody for epithelial cancers.
HE Liu, CL Tseng, S Liu, W Jiang - 2017 - ascopubs.org
e14078 Background: EGFR is a validated target for anti-cancer drug development. Several
anti-EGFR monoclonal antibodies (mAb) are used in clinics, but associated with a variety of …
anti-EGFR monoclonal antibodies (mAb) are used in clinics, but associated with a variety of …