Cohort profile: Tohoku medical megabank project birth and three-generation cohort study (TMM BirThree cohort study): rationale, progress and perspective

S Kuriyama, H Metoki, M Kikuya, T Obara… - International journal …, 2020 - academic.oup.com
Although a large sample size is useful for the elucidation of what is called 'missing
heritability', which is an unexplained part of a total phenotypic variance in a quantitative trait …

[HTML][HTML] Clustering by phenotype and genome-wide association study in autism

A Narita, M Nagai, S Mizuno, S Ogishima… - Translational …, 2020 - nature.com
Autism spectrum disorder (ASD) has phenotypically and genetically heterogeneous
characteristics. A simulation study demonstrated that attempts to categorize patients with a …

[HTML][HTML] Perception of earthquake risks and disaster prevention awareness: A comparison of resident surveys in Sendai, Japan and Seattle, WA, USA

AYE Ahn, H Takikawa, E Maly, A Bostrom… - International Journal of …, 2021 - Elsevier
Abstract Both Sendai City in Japan and Seattle-King County (hereafter referred to as
“Seattle”) in Washington State in the United States are in seismically active areas with high …

[HTML][HTML] Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods

T Obara, M Ishikuro, G Tamiya, M Ueki, C Yamanaka… - Scientific reports, 2018 - nature.com
We investigated whether machine learning methods could potentially identify a subgroup of
persons with autism spectrum disorder (ASD) who show vitamin B6 responsiveness by …

Impact of the great east Japan earthquake on the body mass index of preschool children: a nationwide nursery school survey

H Yokomichi, W Zheng, H Matsubara, M Ishikuro… - BMJ open, 2016 - bmjopen.bmj.com
Objective To evaluate the impact of the 2011 great east Japan earthquake on body mass
index (BMI) of preschool children. Design Retrospective cohort study and ecological study …

Relationships among personality traits, metabolic syndrome, and metabolic syndrome scores: The Kakegawa cohort study

H Ohseto, M Ishikuro, M Kikuya, T Obara… - Journal of …, 2018 - Elsevier
Objective Metabolic syndrome and the presence of metabolic syndrome components are
risk factors for cardiovascular disease (CVD). However, the association between personality …

Carnosine and anserine in chicken can quench toxic acrylamide under cooking conditions: Mass spectrometric studies on adduct formation and characterization

A Takama, H Matsubara, SH Lee, T Oe - Food Chemistry, 2020 - Elsevier
Acrylamide (AA) is a toxic industrial chemical but is also found in heated potato foods such
as French fries due to the Maillard reaction between amino acids and reducing sugars …

Association between bacterial community structures and mortality of fish larvae in intensive rearing systems

G Nakase, Y Nakagawa, S Miyashita, T Nasu… - Fisheries Science, 2007 - Springer
Bacterial community structures were analyzed in water used for rearing fish larvae by
fluorescence in situ hybridization. In Experiment 1, red sea bream Pagrus major larvae were …

[HTML][HTML] Disease prevalence among nursery school children after the Great East Japan earthquake

M Ishikuro, H Matsubara, M Kikuya, T Obara, Y Sato… - BMJ Global …, 2017 - gh.bmj.com
Objective To investigate the relationship between personal experience of the Great East
Japan Earthquake and various disease types among nursery school children. Design We …

Differences in branched-chain amino acid to tyrosine ratio (BTR) among etiologies of chronic liver disease progression compared to healthy adults.

M Mino, A Sano, E Kakazu, H Matsubara… - Journal of …, 2024 - Springer
Background The branched-chain amino acids (BCAAs) to tyrosine (Tyr) ratio (BTR) test is
used to evaluate the progression of chronic liver disease (CLD). However, the differences …