Immunoassay for human serum hepcidin

T Ganz, G Olbina, D Girelli, E Nemeth… - Blood, The Journal …, 2008 - ashpublications.org
We developed and validated the first serum enzyme-linked immunosorbent assay for
hepcidin, the principal iron-regulatory hormone that has been very difficult to measure. In …

Hepcidin—a potential novel biomarker for iron status in chronic kidney disease

…, HJ Wang, M Westerman, G Olbina… - Clinical Journal of the …, 2009 - journals.lww.com
Hepcidin—A Potential Novel Biomarker for Iron Status in Chro... : Clinical Journal of the
American Society of Nephrology Hepcidin—A Potential Novel Biomarker for Iron Status in …

[HTML][HTML] Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization

…, RC Hider, V Koliaraki, A Mamalaki, G Olbina… - …, 2009 - ncbi.nlm.nih.gov
The recently discovered iron regulatory peptide hormone hepcidin holds promise as a novel
biomarker in iron metabolism disorders. To date, various mass spectrometry and …

Testosterone suppresses hepcidin in men: a potential mechanism for testosterone-induced erythrocytosis

…, R Feng, T Travison, M Li, G Olbina… - The Journal of …, 2010 - academic.oup.com
Context: The mechanisms by which testosterone increases hemoglobin and hematocrit are
unknown. Objective: The aim was to test the hypothesis that testosterone-induced increase …

[HTML][HTML] A novel hypoxia-inducible factor− prolyl hydroxylase inhibitor (GSK1278863) for anemia in CKD: a 28-day, phase 2A randomized trial

…, B Johnson, C Oei, M Westerman, G Olbina… - American Journal of …, 2016 - Elsevier
Background Anemia associated with chronic kidney disease (CKD) often requires treatment
with recombinant human erythropoietin (EPO). Hypoxia-inducible factor− prolyl hydroxylase …

[HTML][HTML] Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young women

…, RP Glahn, M Ariza-Nieto, J Inglis, G Olbina… - The American journal of …, 2009 - Elsevier
Background: Hepcidin is a key regulator of iron homeostasis, but to date no studies have
examined the effect of hepcidin on iron absorption in humans. Objective: Our objective was …

Toward worldwide hepcidin assay harmonization: identification of a commutable secondary reference material

…, H Drakesmith, M Fillet, G Olbina… - Clinical …, 2016 - academic.oup.com
BACKGROUND Absolute plasma hepcidin concentrations measured by various procedures
differ substantially, complicating interpretation of results and rendering reference intervals …

Iron absorption in dysmetabolic iron overload syndrome is decreased and correlates with increased plasma hepcidin

M Ruivard, F Lainé, T Ganz, G Olbina, M Westerman… - Journal of …, 2009 - Elsevier
BACKGROUND/AIMS: The dysmetabolic iron overload syndrome (DIOS) is a common
disorder but its origin remains unclear. METHODS: A case-control study was conducted to …

Provisional standardization of hepcidin assays: creating a traceability chain with a primary reference material, candidate reference method and a commutable …

…, A Castagna, M Herkert, O Itkonen, G Olbina… - Clinical Chemistry and …, 2019 - degruyter.com
Background Hepcidin concentrations measured by various methods differ considerably,
complicating interpretation. Here, a previously identified plasma-based candidate secondary …

[PDF][PDF] Hepcidin and disordered mineral metabolism in chronic kidney disease

C Carvalho, T Isakova, G Collerone, G Olbina… - Clinical …, 2011 - researchgate.net
Background; Hepcidin regulates iron homeostasis by blocking iron absorption from the gut
and iron release from macrophage and hepatocyte stores. Hepcidin levels are elevated in …