Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

…, T Seitz, S Li, P Janosch, B McFerran, C Kaiser, F Fee… - Nature, 1999 - nature.com
Raf-1 phosphorylates and activates MEK-1, a kinase that activates the extracellular signal
regulated kinases (ERK). This kinase cascade controls the proliferation and differentiation of …

Positive-and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway

SY Shin, O Rath, SM Choo, F Fee… - Journal of cell …, 2009 - journals.biologists.com
The Ras-Raf-MEK-ERK pathway (or ERK pathway) is an important signal transduction
system involved in the control of cell proliferation, survival and differentiation. However, the …

Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis

RJ Akhurst, F Fee, A Balmaint - Nature, 1988 - nature.com
Tumour promoters induce a wide spectrum of morphological and biochemical alterations
when applied to mouse epidermis in vivo 1. These include the induction of RNA (ref. 2), DNA …

[BOOK][B] Loaded wheel testers in the United States: State of the practice

LA Cooley, PS Kandhal, MS Buchanan, F Fee, A Epps - 2000 - eng.auburn.edu
Loaded wheel testers (LWT) are becoming increasingly popular with transportation
agencies as they seek to identify hot mix asphalt mixtures that may be prone to rutting. This …

Profiles of cognitive functioning in chronic spinal cord injury and the role of moderating variables

…, KY Haaland, RM Swanda, F Fee… - Journal of the …, 1997 - cambridge.org
A traumatic spinal cord injury (SCI) is accompanied by a documented moderate to severe
head injury in significant numbers of SCI patients. In a previous study (Dowler et al., 1995) …

Distinct genetic loci control development of benign and malignant skin tumours in mice

H Nagase, S Bryson, H Cordell, CJ Kemp, F Fee… - Nature …, 1995 - nature.com
Genetic susceptibility to chemically induced skin cancer in mice is controlled by multiple
unlinked genetic loci. Mus spretus mice have dominant resistance genes which confer …

[PDF][PDF] Fueling the future: the prospects for Russian oil and gas

F Hill, F Fee - Demokratizatsiya, 2002 - demokratizatsiya.pub
Following the terrorist attacks against the United States on 11 September 2001, growing
tensions in American relations with Middle East states coincided with the efforts of the …

Study to promote innovation in rural integrated telepsychiatry (SPIRIT): rationale and design of a randomized comparative effectiveness trial of managing complex …

JC Fortney, PJ Heagerty, AM Bauer… - Contemporary Clinical …, 2020 - Elsevier
Objective Managing complex psychiatric disorders like PTSD and bipolar disorder is
challenging in Federally Qualified Health Centers (FQHCs) delivering care to US residents …

Chemical induction of oncogene mutations and growth factor activity in mouse skin carcinogenesis.

…, K Brown, M Ramsden, RJ Akhurst, F Fee… - Environmental …, 1989 - ehp.niehs.nih.gov
The goal of understanding the molecular basis of human tumor development has been
greatly facilitated by the use of animal model systems in which the etiology of tumor …

Regulation of human myoblast differentiation by PEBP4

R Garcia, J Grindlay, O Rath, F Fee, W Kolch - EMBO reports, 2009 - embopress.org
The RAF–MEK–ERK pathway regulates both myoblast proliferation and differentiation;
however, it is unclear how these events are coordinated. Here, we show that human …