User profiles for "author:Ene Choo Tan"
Ene-Choo TanKK Women's and Children's Hospital Verified email at kkh.com.sg Cited by 3619 |
[HTML][HTML] Review and consensus on pharmacogenomic testing in psychiatry
The implementation of pharmacogenomic (PGx) testing in psychiatry remains modest, in part
due to divergent perceptions of the quality and completeness of the evidence base and …
due to divergent perceptions of the quality and completeness of the evidence base and …
[HTML][HTML] Clinical application of next-generation sequencing for Mendelian diseases
Over the past decade, next-generation sequencing (NGS) has led to an exponential
increase in our understanding of the genetic basis of Mendelian diseases. NGS allows for …
increase in our understanding of the genetic basis of Mendelian diseases. NGS allows for …
PURA syndrome: clinical delineation and genotype-phenotype study in 32 individuals with review of published literature
Background De novo mutations in PURA have recently been described to cause PURA
syndrome, a neurodevelopmental disorder characterised by severe intellectual disability …
syndrome, a neurodevelopmental disorder characterised by severe intellectual disability …
A118G single nucleotide polymorphism of human μ-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after …
AT Sia, Y Lim, ECP Lim, RWC Goh, HY Law… - The Journal of the …, 2008 - pubs.asahq.org
Background Previous studies have shown that genetic variability at position 118 of the
human mu-opioid receptor gene altered patients' response to intravenous morphine. The …
human mu-opioid receptor gene altered patients' response to intravenous morphine. The …
Mu opioid receptor gene polymorphisms and heroin dependence in Asian populations
The distribution of three polymorphisms of the mu opioid receptor gene (OPRM1) was
investigated in four different Asian populations, and in heroin-dependent subjects deriving …
investigated in four different Asian populations, and in heroin-dependent subjects deriving …
Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain
Background Morphine consumption can vary widely between individuals even for identical
surgical procedures. As mu-opioid receptor (OPRM1) is known to modulate pain perception …
surgical procedures. As mu-opioid receptor (OPRM1) is known to modulate pain perception …
[HTML][HTML] Ethnic differences in pain perception and patient-controlled analgesia usage for postoperative pain
There are reports suggesting that sensitivity to and tolerance of both clinical and
experimental pain differ among ethnic groups. We examined self-rated pain score and …
experimental pain differ among ethnic groups. We examined self-rated pain score and …
Combined analysis of 635 patients confirms an age-related association of the serotonin 2A receptor gene with tardive dyskinesia and specificity for the non-orofacial …
Tardive dyskinesia (TD) is an important limiting factor in the use of typical antipsychotic
drugs. Genetic variability in the serotonin 2A (5-HT2A) receptor may influence risk for TD but …
drugs. Genetic variability in the serotonin 2A (5-HT2A) receptor may influence risk for TD but …
Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study
T Suhitharan, TPT Pham, H Chen… - Neuropsychiatric …, 2016 - Taylor & Francis
Aim The aim of this study was to investigate the role of peripartum analgesic and
psychological factors that may be related to postpartum depression (PPD). Methods This …
psychological factors that may be related to postpartum depression (PPD). Methods This …
[HTML][HTML] Germline AGO2 mutations impair RNA interference and human neurological development
D Lessel, DM Zeitler, MRF Reijnders… - Nature …, 2020 - nature.com
ARGONAUTE-2 and associated miRNAs form the RNA-induced silencing complex (RISC),
which targets mRNAs for translational silencing and degradation as part of the RNA …
which targets mRNAs for translational silencing and degradation as part of the RNA …