This is a clinical text about the commonest physical disability-the cerebral palsies. It follows
up on the authors' earlier work The Epidemiology of the Cerebral Palsies, and its focus is still …

This is the second volume dealing with a survey conducted in 1958 covering a national
sample of over 17000 births and an additional 7000 perinatal and late neonatal deaths …

AIMS To investigate socioeconomic inequalities in the risk of congenital anomalies, focusing
on risk of specific anomaly subgroups. METHODS A total of 858 cases of congenital …

Objectives: To revise the estimates of maternal age specific live birth prevalence of Down's
syndrome in the absence of antenatal screening and selective termination using newly …

A cohort study of 1425 persons with Down's syndrome (DS), and of their parents (447
mothers, 435 fathers) and siblings (1176), was set up to investigate death rates from various …

Objectives To describe trends in the numbers of Down's syndrome live births and antenatal
diagnoses in England and Wales from 1989 to 2008. Design and setting The National Down …

Data from the National Down Syndrome Cytogenetic Register is used to describe the
cytogenetics and epidemiology of registered cases. The register comprises notifications from …

Objective To investigate possible multigenerational influences on birthweight. Design Data
from the longitudinal study of one week's births in 1958 up to the age of 23 years, the British …

Mortality and cancer incidence were assessed in a cohort of 1373 patients with numerical
sex chromosome abnormalities diagnosed at three cytogenetics centres in Britain during …

The birth prevalence of sex chromosome trisomies (SCT), that is individuals with an XYY,
XXY or XXX sex chromosome constitution, is traditionally based on six surveys of unselected …