User profiles for "author:D MCDONALD"

Daniel McDonald

- Verified email at ucsd.edu - Cited by 99281

Donald M McDonald

- Verified email at ucsf.edu - Cited by 46450

Best practices for analysing microbiomes

…, T Kosciolek, LI McCall, D McDonald… - Nature Reviews …, 2018 - nature.com
Complex microbial communities shape the dynamics of various environments, ranging from
the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies …

Imaging of angiogenesis: from microscope to clinic

DM McDonald, PL Choyke - Nature medicine, 2003 - nature.com
Advances in imaging are transforming our understanding of angiogenesis and the
evaluation of drugs that stimulate or inhibit angiogenesis in preclinical models and human …

[HTML][HTML] Mechanisms of adverse effects of anti-VEGF therapy for cancer

T Kamba, DM McDonald - British journal of cancer, 2007 - nature.com
Advances in understanding the role of vascular endothelial growth factor (VEGF) in normal
physiology are giving insight into the basis of adverse effects attributed to the use of VEGF …

[HTML][HTML] Safety, activity, and immune correlates of anti–PD-1 antibody in cancer

…, M Jure-Kunkel, S Agrawal, D McDonald… - … England Journal of …, 2012 - Mass Medical Soc
Background Blockade of programmed death 1 (PD-1), an inhibitory receptor expressed by T
cells, can overcome immune resistance. We assessed the antitumor activity and safety of …

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

…, M Maher, C Marotz, BD Martin, D McDonald… - Nature …, 2019 - nature.com
To the Editor—Rapid advances in DNA-sequencing and bioinformatics technologies in the
past two decades have substantially improved understanding of the microbial world. This …

Direct evidence for neutrino flavor transformation from neutral-current interactions in the Sudbury Neutrino Observatory

QR Ahmad, RC Allen, TC Andersen, JD Anglin… - Physical review …, 2002 - APS
Observations of neutral-current ν interactions on deuterium in the Sudbury Neutrino
Observatory are reported. Using the neutral current (NC), elastic scattering, and charged …

QIIME allows analysis of high-throughput community sequencing data

…, JE Koenig, RE Ley, CA Lozupone, D McDonald… - Nature …, 2010 - nature.com
To the Editor: High-throughput sequencing is revolutionizing microbial ecology studies.
Efforts like the Human Microbiome Projects 1 and the US National Ecological Observatory …

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

…, J Zaneveld, JG Caporaso, D McDonald… - Nature …, 2013 - nature.com
Profiling phylogenetic marker genes, such as the 16S rRNA gene, is a key tool for studies of
microbial communities but does not provide direct evidence of a community's functional …

[PDF][PDF] The treatment-naive microbiome in new-onset Crohn's disease

…, AD Kostic, C Luo, A González, D McDonald… - Cell host & …, 2014 - cell.com
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked
to host pathways that implicate an underlying role for aberrant immune responses to …

Measurement of day and night neutrino energy spectra at SNO and constraints on neutrino mixing parameters

QR Ahmad, RC Allen, TC Andersen, JD Anglin… - Physical Review Letters, 2002 - APS
Abstract The Sudbury Neutrino Observatory (SNO) has measured day and night solar
neutrino energy spectra and rates. For charged current events, assuming an undistorted 8 B …