We previously described a method for isolating murine hematopoietic stem cells capable of
reconstituting lethally irradiated recipients, which depends solely on dual-wavelength flow …

Diamond-Blackfan anemia (DBA), a congenital bone-marrow-failure syndrome, is
characterized by red blood cell aplasia, macrocytic anemia, clinical heterogeneity, and …

Mice with monoallelic inactivation of the CBP gene develop highly penetrant, multilineage
defects in hematopoietic differentiation and, with advancing age, an increased incidence of …

Mutations in numerous genes encoding ribosomal proteins (RPs) occur in 50%–70% of
individuals with Diamond-Blackfan anemia (DBA), establishing the disease as a …

Diamond-Blackfan anemia (DBA) is a rare congenital red-cell aplasia characterized by
anemia, bone-marrow erythroblastopenia, and congenital anomalies and is associated with …

Ribosomal protein haploinsufficiency occurs in diverse human diseases including Diamond-
Blackfan anemia (DBA),, congenital asplenia and T cell leukemia. Yet, how mutations in …

Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure syndrome
characterized by anemia, congenital abnormalities, and cancer predisposition. Small …

Diamond-Blackfan anemia (DBA), an inherited bone marrow failure syndrome characterized
by anemia that usually presents before the first birthday or in early childhood, is associated …

Diamond-Blackfan anemia (DBA) is a rare bone marrow failure disorder that affects 7 out of
1,000,000 live births and has been associated with mutations in components of the …

The process of blood cell formation, by which a small number of self-renewing stem cells
give rise to lineage committed pro-genitor cells that subsequently proliferateand differentiate …