Newly synthesized histone H4 is deposited in a diacetylated isoform in a wide variety of
organisms. In Tetrahymena a specific pair of residues, lysines 4 and 11, have been shown to …

Abstract Treatment of human endothelial cells with cytokines such as interleukin-1, tumor
necrosis factor-alpha (TNF-alpha) or interferon-gamma induces the expression of specific …

The in utero availability of methyl donors, such as choline, may modify fetal epigenetic marks
and lead to sustainable functional alterations throughout the life course. The hypothalamic …

• To evaluate the use of hypertonic saline/dextran solutions in the prehospital resuscitation
of severely injured patients, we administered 250 mL of either 7.5% sodium chloride/dextran …

Although the processes of climate change are not completely understood, an important
causal candidate is variation in total solar output. Reported cycles in various climate-proxy …

Background: In 1998 choline Adequate Intakes of 425 and 450 mg/d were established for
nonpregnant and pregnant women, respectively. However, to our knowledge, no dose …

1 Department of Agronomy, Kansas State University, Manhattan, KS 66506. is sensitive and
well characterized (6-9). Furthermore, both liquid chromatography (6, 10-12) and gas …

Small volume infusions of hypertonic saline combined with dextran are very effective in
resuscitating animals that have been subjected to hemorrhagic shock, and seem to be …

The hydroxymethyl group of serine is a primary source of tetrahydrofolate (THF)-activated
one-carbon units that are required for the synthesis of purines and thymidylate and for S …

Background: Although biomarkers of choline metabolism are altered by pregnancy, little is
known about the influence of human pregnancy on the dynamics of choline-related …