Procedural pain and brain development in premature newborns
S Brummelte, RE Grunau, V Chau, KJ Poskitt… - Annals of …, 2012 - Wiley Online Library
Objective: Preterm infants are exposed to multiple painful procedures in the neonatal
intensive care unit (NICU) during a period of rapid brain development. Our aim was to …
intensive care unit (NICU) during a period of rapid brain development. Our aim was to …
Neonatal pain, parenting stress and interaction, in relation to cognitive and motor development at 8 and 18 months in preterm infants
RE Grunau, MF Whitfield, J Petrie-Thomas, AR Synnes… - Pain, 2009 - Elsevier
Procedural pain in the neonatal intensive care unit triggers a cascade of physiological,
behavioral and hormonal disruptions which may contribute to altered neurodevelopment in …
behavioral and hormonal disruptions which may contribute to altered neurodevelopment in …
[HTML][HTML] Neonatal pain-related stress predicts cortical thickness at age 7 years in children born very preterm
Background Altered brain development is evident in children born very preterm (24–32
weeks gestational age), including reduction in gray and white matter volumes, and thinner …
weeks gestational age), including reduction in gray and white matter volumes, and thinner …
Invasive procedures in preterm children: brain and cognitive development at school age
BACKGROUND: Very preterm infants (born 24–32 weeks' gestation) undergo numerous
invasive procedures during neonatal care. Repeated skin-breaking procedures in rodents …
invasive procedures during neonatal care. Repeated skin-breaking procedures in rodents …
Slower postnatal growth is associated with delayed cerebral cortical maturation in preterm newborns
Slower postnatal growth is an important predictor of adverse neurodevelopmental outcomes
in infants born preterm. However, the relationship between postnatal growth and cortical …
in infants born preterm. However, the relationship between postnatal growth and cortical …
Cortisol levels in former preterm children at school age are predicted by neonatal procedural pain-related stress
S Brummelte, CMY Chau, IL Cepeda… - …, 2015 - Elsevier
Early life stress can alter hypothalamic pituitary adrenal (HPA) axis function. Differences in
cortisol levels have been found in preterm infants exposed to substantial procedural stress …
cortisol levels have been found in preterm infants exposed to substantial procedural stress …
Neonatal pain in relation to postnatal growth in infants born very preterm
Procedural pain is associated with poorer neurodevelopment in infants born very preterm (⩽
32weeks gestational age), however, the etiology is unclear. Animal studies have …
32weeks gestational age), however, the etiology is unclear. Animal studies have …
Variations in intraventricular hemorrhage incidence rates among Canadian neonatal intensive care units
AR Synnes, LY Chien, A Peliowski, R Baboolal… - The Journal of …, 2001 - Elsevier
Objectives: To examine the variation in intraventricular hemorrhage (IVH) incidence among
neonatal intensive care units and identify potentially modifiable risk factors. Study design …
neonatal intensive care units and identify potentially modifiable risk factors. Study design …
Neonatal pain and infection relate to smaller cerebellum in very preterm children at school age
Objective To examine whether specific neonatal factors differentially influence cerebellar
subregional volumes and to investigate relationships between subregional volumes and …
subregional volumes and to investigate relationships between subregional volumes and …
Parent behaviors moderate the relationship between neonatal pain and internalizing behaviors at 18 months corrected age in children born very prematurely
Children born very preterm (⩽ 32 weeks gestation) exhibit greater internalizing
(anxious/depressed) behaviors compared to term-born peers as early as 2 years corrected …
(anxious/depressed) behaviors compared to term-born peers as early as 2 years corrected …