Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts

MO Goodarzi, MR Jones, X Li, AK Chua… - Journal of medical …, 2012 - jmg.bmj.com
Background Polycystic ovary syndrome (PCOS) is a complex endocrine disorder with a
strong familial component. PCOS is characterised by hyperandrogenaemia and irregular …

Early embryonic androgen exposure induces transgenerational epigenetic and metabolic changes

N Xu, AK Chua, H Jiang, NA Liu… - Molecular …, 2014 - academic.oup.com
Androgen excess is a central feature of polycystic ovary syndrome (PCOS), which affects 6%
to 10% of young women. Mammals exposed to elevated androgens in utero develop PCOS …

Metabolic and cardiovascular genes in polycystic ovary syndrome: a candidate-wide association study (CWAS)

MR Jones, AK Chua, EA Mengesha, KD Taylor… - Steroids, 2012 - Elsevier
The role of metabolic disturbance in polycystic ovary syndrome (PCOS) has been well
established, with insulin resistance and the resulting compensatory hyperinsulinemia …

Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage

AK Chua, R Azziz, MO Goodarzi - MHR: Basic science of …, 2012 - academic.oup.com
Abstract Cytochrome P450-C17 enzyme (CYP17) is an important component of the
androgen synthesis pathway, a pathway that is dysfunctional in polycystic ovary syndrome …

Steroidogenic Regulatory Factor FOS Is Underexpressed in Polycystic Ovary Syndrome (PCOS) Adipose Tissue and Genetically Associated with PCOS Susceptibility

…, G Chazenbalk, N Xu, AK Chua… - The Journal of …, 2012 - academic.oup.com
Context: Polycystic ovary syndrome (PCOS) is a heterogeneous common genetic disorder
characterized by hyperandrogenemia and insulin resistance. Alterations in gene expression …

[PDF][PDF] Journal of Industrial Information Integration

DS Cochrana, MU Jafria, AK Chua… - Journal of Industrial …, 2016 - academia.edu
abstract The definition of system metrics is crucial to determine if a manufacturing system
design is truly effective because inappropriate metrics can lead to ineffective or improperly …

Three Dimensional Image Reconstruction From Longwave Holograms-A Feasibility Study

NH Farhat, AK Chua - Coherent Optical Processing, 1974 - spiedigitallibrary.org
This paper concerns itself with the investigation of a method for solving the long-standing
problem of longitudinal image distortion encountered in longwave (microwave or acoustic) …

Three-Dimensional Image Reconstruction from Longwave Holograms A Feasibility Study

NH Farhat, AK Chua - Optical Engineering, 1975 - spiedigitallibrary.org
This paper concerns itself with the investigation of a method for solving the longstanding
problem of longitudinal image distortion encountered in longwave (microwave or acoustic) …

G455 (P) Improving access and quality of diagnostic services in a developmental and behavioural service for pre–school children–the triage–track model

S Singhal, HH Lim, AK Chua, LM Daniel, SB Lim - 2015 - adc.bmj.com
Aim The Department of Child Development (DCD) at our hospital is the major diagnostic and
interim intervention service provider for pre–school children with developmental and …

Design of an end-to-end taxi transport claims system–part 1

AK Chua - 2009 - dr.ntu.edu.sg
The standard procedure for making a claim generally has to go through a formal request,
after which it will be put through a lengthy approval process before the budget is allocated …