Background: Distal renal tubular acidosis (dRTA) caused by mutations of the SLC4A1 gene
encoding the erythroid and kidney isoforms of anion exchanger 1 (AE1 or band 3) has a …

The AE1 gene encodes band 3 Cl-/HCO3-exchangers that are expressed both in the
erythrocyte and in the acid-secreting, type A intercalated cells of the kidney. Kidney AE1 …

Studies of the renal involvement in thalassemic syndromes have been varied and few. This
study was designed to define the renal abnormalities associated with β-thalassemia and to …

Eight patients with the middle aortic syndrome are described. They were aged 2 months to
14 years at diagnosis; follow up was one to 11 years. Clinical presentations included …

Shortened red cell life span and excess iron cause functional and physiological
abnormalities in various organ systems in thalassemia patients. In an earlier study, we …

Background: Mutations in the SLC4A1 gene have been found to cause either autosomal
dominant (AD) or autosomal recessive (AR) distal renal tubular acidosis (dRTA). The …

Objectives: To define the patterns of clinicopathologic findings and to identify the risk factors
for renal failure and mortality of childhood-onset systemic lupus erythematosus (SLE) in …

Background Bladder and bowel dysfunction (BBD) is a common disorder in children that is
often associated with psychosocial and behavioral problems. Data specific to BBD in Asian …

Background Rapidly progressive glomerulonephritis (RPGN), defined as acute nephritic
syndrome with dramatic loss of renal function within a few months, is associated with …

Objective: Assess the relation of age and sex in vesico ureteral reflux (VUR) and renal
scarring and the relation of VUR and renal scarring in childhood urinary tract infection …