Background Early rapid fluid resuscitation (boluses) in African children with severe
febrileillnesses increases the 48-hour mortality by 3.3% compared with controls (nobolus) …

Background Mortality in paediatric emergency care units in Africa often occurs within the first
24 h of admission and remains high. Alongside effective triage systems, a practical clinical …

Abstract Background The World Health Organization recommends not performing
transfusions in African children hospitalized for uncomplicated severe anemia (hemoglobin …

Purpose The life-saving role of oxygen therapy in African children with severe pneumonia is
not yet established. Methods The open-label fractional-factorial COAST trial randomised …

Background Severe anemia (hemoglobin level,< 6 g per deciliter) is a leading cause of
hospital admission and death in children in sub-Saharan Africa. The World Health …

Background: In Africa, the clinical syndrome of pneumonia remains the leading cause of
morbidity and mortality in children in the post-neonatal period. This represents a significant …

Case fatality among African children with severe acute malnutrition remains high. We report
a 3-arm pilot trial in 58 Ugandan children, comparing feeds targeting disordered …

Abstract Background In sub-Saharan Africa, where infectious diseases and nutritional
deficiencies are common, severe anaemia is a common cause of paediatric hospital …

Background Severe anaemia is a leading cause of paediatric admission to hospital in Africa;
post-discharge outcomes remain poor, with high 6-month mortality (8%) and re-admission …

Importance Mortality among African children hospitalized with severe malnutrition remains
high, with sudden, unexpected deaths leading to speculation about potential cardiac …