This article reviews recent findings on the global epidemiology of healthcare-
acquired/associated (HA), community-acquired/associated (CA) and livestock-associated …

Background Animals can act as a reservoir and source for the emergence of novel meticillin-
resistant Staphylococcus aureus (MRSA) clones in human beings. Here, we report the …

The widespread use of antibiotics in association with high-density clinical care has driven
the emergence of drug-resistant bacteria that are adapted to thrive in hospitalized patients …

Staphylococcus aureus isolates carrying the genes that encode for Panton-Valentine
leucocidin (PVL), a highly potent toxin, have been responsible for recent outbreaks of severe …

Whole-genome sequencing (WGS) could potentially provide a single platform for extracting
all the information required to predict an organism's phenotype. However, its ability to …

Background The spread of drug-resistant bacterial pathogens poses a major threat to global
health. It is widely recognised that the widespread use of antibiotics has generated selective …

During the 1950s, the notorious penicillin-resistant clone of Staphylococcus aureus known
as phage type 80/81 emerged and caused serious hospital-acquired and community …

Objectives To investigate the prospects of newly available benchtop sequencers to provide
rapid whole-genome data in routine clinical practice. Next-generation sequencing has the …

The importance of livestock as a source of bacterial pathogens with the potential for
epidemic spread in human populations is unclear. In recent years, there has been a global …

Current DNA amplification-based typing methods for bacterial pathogens often lack
interlaboratory reproducibility. In this international study, DNA sequence-based typing of the …