User profiles for "author:A K Shetty"

Dr. Ashok K. Shetty

Associate Director and Professor, Institute for Regen Med, Texas A&M Health Science …
Verified email at tamu.edu
Cited by 22867

Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders

R Upadhya, W Zingg, S Shetty, AK Shetty - Journal of controlled release, 2020 - Elsevier
Extracellular vesicles (EVs) released by neural cells play an essential role in brain
homeostasis and the crosstalk between neural cells and the periphery. EVs are diverse …

Progress in neuroprotective strategies for preventing epilepsy

MM Acharya, B Hattiangady, AK Shetty - Progress in neurobiology, 2008 - Elsevier
Neuroprotection is increasingly considered as a promising therapy for preventing and
treating temporal lobe epilepsy (TLE). The development of chronic TLE, also termed as …

Hippocampal neurogenesis and neural stem cells in temporal lobe epilepsy

R Kuruba, B Hattiangady, AK Shetty - Epilepsy & Behavior, 2009 - Elsevier
Virtually all mammals, including humans, exhibit neurogenesis throughout life in the
hippocampus, a learning and memory center in the brain. Numerous studies in animal …

Lactobacillus Sepsis Associated With Probiotic Therapy

MH Land, K Rouster-Stevens, CR Woods… - …, 2005 - publications.aap.org
Probiotic strains of lactobacilli are increasingly being used in clinical practice because of
their many health benefits. Infections associated with probiotic strains of lactobacilli are …

Efficacy of doublecortin as a marker to analyse the absolute number anddendritic growth of newly generated neurons in the adult dentate gyrus

MS Rao, AK Shetty - European Journal of Neuroscience, 2004 - Wiley Online Library
Abstract Doublecortin (DCX), a microtubule‐associated phosphoprotein, has been recently
utilized as a marker of newly born neurons in the adult dentate gyrus (DG). Nonetheless, it is …

Stem/progenitor cell proliferation factors FGF‐2, IGF‐1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes

AK Shetty, B Hattiangady, GA Shetty - Glia, 2005 - Wiley Online Library
Dentate neurogenesis, important for learning and memory, declines dramatically by middle
age. Although studies have shown that this age‐related decrease can be reversed to some …

Characterization of neuronal/glial differentiation of murine adipose-derived adult stromal cells

KM Safford, SD Safford, JM Gimble, AK Shetty… - Experimental …, 2004 - Elsevier
Neural tissue has limited capacity for intrinsic repair after injury, and the identification of
alternate sources of neuronal stem cells has broad clinical potential. Preliminary studies …

Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI

D Kim, H Nishida, SY An, AK Shetty… - Proceedings of the …, 2016 - National Acad Sciences
Extracellular vesicles (EVs) secreted by cells present an attractive strategy for developing
new therapies, but progress in the field is limited by several issues: The quality of the EVs …

Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus

Q Long, D Upadhya, B Hattiangady… - Proceedings of the …, 2017 - National Acad Sciences
Status epilepticus (SE), a medical emergency that is typically terminated through
antiepileptic drug treatment, leads to hippocampus dysfunction typified by …

Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus

B Hattiangady, MS Rao, AK Shetty - Neurobiology of disease, 2004 - Elsevier
While it is clear that acute hippocampal injury or status epilepticus increases the production
of new neurons in the adult dentate gyrus (DG), the effects of chronic epilepsy on dentate …