Accurately administering oral medication to children isn't child's play

Arch Dis Child. 2012 Sep;97(9):838-41. doi: 10.1136/archdischild-2012-301850.

Abstract

Objective: Parents administer oral medications with various measuring devices including metal teaspoons, calibrated spoons and oral syringes. We aimed to determine which was the most accurate.

Design: Self-controlled, non-randomised, experimental study.

Setting: Caregivers attending paediatric outpatient clinics.

Methodology: Caregivers measured 5 ml of 120 mg/5 ml paracetamol suspension using a 5.0 ml metal teaspoon, 5.0 ml calibrated spoon and 5.0 ml oral syringe. Samples were weighed and converted to mls.

Main outcome measures: The mean volume and variance of volumes were measured for each device.

Results: We recruited 277 caregivers (98% parents). Volumes measured ranged from 0.83-6.52 ml. Accuracy did not vary with caregivers' age, gender, instrument preference, number and age of children. The mean volumes measured with the oral syringe (95% CI 5.09 to 5.17 ml) and metal spoon (95% CI 3.90 to 4.08 ml) were significantly different to the desired 5 ml volume (p<0.0001), dissimilar to the mean volume measured using the calibrated spoon (95% CI 4.91 to 5.09 ml, p=0.99). The variance of volumes measured with the oral syringe (SD 0.348 ml) was significantly smaller (p<0.0001) than that measured using a calibrated spoon (SD 0.762 ml) or metal spoon (SD 0.749 ml).

Conclusions: The calibrated spoon was the most accurate producing a mean volume of 5 ml, while the oral syringe had the smallest variance. The increased variability of calibrated or metal spoons may result in under or overdosing especially when administering drugs with a narrow therapeutic window. Health care professionals must make a case-by-case decision regarding which device is preferable depending on the medication in question. Parental education could improve measuring accuracy.

MeSH terms

  • Administration, Oral
  • Adolescent
  • Adult
  • Aged
  • Caregivers
  • Child
  • Child, Preschool
  • Equipment and Supplies / standards*
  • Female
  • Humans
  • Male
  • Medication Errors / prevention & control
  • Middle Aged
  • Parents
  • Pharmaceutical Solutions / administration & dosage*
  • Young Adult

Substances

  • Pharmaceutical Solutions