Abstract
We describe two cases of neonatal meningitis due to Gram-negative bacilli treated successfully with ciprofloxacin. Examination of serial samples of cerebrospinal fluid indicated the effect of meningeal inflammation on penetration of this drug into the CSF.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Ciprofloxacin / cerebrospinal fluid*
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Ciprofloxacin / therapeutic use*
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Escherichia coli Infections / cerebrospinal fluid
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Escherichia coli Infections / drug therapy*
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Flavobacterium / isolation & purification
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Gram-Negative Bacterial Infections / cerebrospinal fluid
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Gram-Negative Bacterial Infections / drug therapy*
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Humans
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Infant, Newborn
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Male
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Meningitis, Bacterial / cerebrospinal fluid
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Meningitis, Bacterial / drug therapy*