Gastro-oesophageal reflux and feeding problems after gastrostomy in children with severe neurological impairment

Dev Med Child Neurol. 1995 Apr;37(4):320-9. doi: 10.1111/j.1469-8749.1995.tb12010.x.

Abstract

This study evaluated the effect of percutaneous endoscopic gastrostomy (PEG) on the feeding problems and gastro-oesophageal reflux (GOR) of 30 consecutive children with severe neurological impairment who had PEG between October 1990 and March 1993. Evaluation was by questionnaire, clinical history, examination, 24-hour oesophageal pH monitoring and endoscopy. Gastrostomy placement significantly reduced feeding time, feed-related choking episodes and frequency of chest infections. Family stress was significantly reduced in two-thirds of cases. Significant weight-gain occurred. The clinical severity of GOR was significantly increased in eight patients and fundoplication was required in five. 24-hour oesophageal pH measurements before PEG did not reliably predict subsequently increased GOR. Seven patients died, but their deaths were apparently unrelated to GOR. PEG effectively provides nutrition, improves feed-related stresses, but may exacerbate GOR.

MeSH terms

  • Adolescent
  • Body Weight
  • Child
  • Deglutition Disorders / etiology
  • Deglutition Disorders / therapy*
  • Enteral Nutrition / methods*
  • Esophagitis / complications
  • Esophagitis / physiopathology
  • Female
  • Gastroesophageal Reflux / diagnosis*
  • Gastroesophageal Reflux / etiology
  • Gastrostomy / methods*
  • Humans
  • Male
  • Nervous System Diseases / complications
  • Nervous System Diseases / physiopathology*
  • Severity of Illness Index
  • Weight Gain