Increased incidence of childhood bacterial meningitis. A 25-year study in a defined population in Sweden

Scand J Infect Dis. 1987;19(1):1-11. doi: 10.3109/00365548709032371.

Abstract

In a retrospective study in Orebro, Sweden 1956-1980, 201 cases of bacterial meningitis in children over the age of 1 month were analysed. The aetiology was Haemophilus influenzae in 123 cases, Neisseria meningitidis in 55 cases and Streptococcus pneumoniae in 19 cases. We registered a significant increase in incidence of H. influenzae meningitis from 5.6 (1956-1965) to 13.0 (1971-1980) per 100,000 children and year (p less than 0.01). The mortality decreased from 19% to 4% during the period studied. This decrease was primarily due to a reduced mortality in hospital later than 12 h after admission. Hearing impairment was the most frequent sequel (10%) and no change in frequency was observed during the 25 years studied. Hearing impairment was registered significantly more often in cases with a late admission to hospital (greater than 48 h) as compared to cases with an earlier admission (p less than 0.001).

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Hearing Disorders / etiology
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Meningitis, Haemophilus / complications
  • Meningitis, Haemophilus / epidemiology*
  • Meningitis, Haemophilus / mortality
  • Meningitis, Meningococcal / complications
  • Meningitis, Meningococcal / epidemiology*
  • Meningitis, Meningococcal / mortality
  • Meningitis, Pneumococcal / complications
  • Meningitis, Pneumococcal / epidemiology*
  • Meningitis, Pneumococcal / mortality
  • Retrospective Studies
  • Sweden