Bacterial meningitis with initial normal cerebrospinal fluid findings

Isr J Med Sci. 1989 Apr;25(4):186-8.

Abstract

Seven pediatric patients with bacterial meningitis but with initial normal cerebrospinal fluid (CSF) findings are presented. They represent 6.5% of all cases with bacterial meningitis seen at our medical center during a 5-year period. In all cases, the duration of symptoms before the initial lumbar puncture was short (6-24 h). The case-fatality rate was 3/7 (43%) compared with 10/100 (10%) among children with abnormal initial CSF, despite early initiation of antibiotics. Bacterial meningitis with an initial normal CSF finding is not rare and may be associated with poor outcome.

MeSH terms

  • Bacterial Infections / cerebrospinal fluid
  • Bacterial Infections / microbiology*
  • Bacterial Infections / mortality
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Meningitis / cerebrospinal fluid
  • Meningitis / microbiology*
  • Meningitis / mortality
  • Retrospective Studies