Acute dysphonia secondary to vocal fold hemorrhage after vardenafil use

Ear Nose Throat J. 2010 Jun;89(6):E21-2.

Abstract

Owing to their vasodilatory effects, the phosphodiesterase-5 inhibitors have become widely used for the treatment of erectile dysfunction. Among the reported adverse events of these agents are epistaxis, variceal bleeding, intracranial hemorrhage, and hemorrhoidal bleeding. We report a case of vocal fold hemorrhage that occurred after vardenafil use in a 31-year-old man who was a professional singer.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Dysphonia / chemically induced*
  • Dysphonia / diagnosis
  • Dysphonia / drug therapy
  • Hemorrhage / chemically induced*
  • Hemorrhage / diagnosis
  • Hemorrhage / drug therapy
  • Humans
  • Imidazoles / adverse effects*
  • Male
  • Phosphodiesterase Inhibitors / adverse effects*
  • Piperazines / adverse effects*
  • Sulfones / adverse effects
  • Triazines / adverse effects
  • Vardenafil Dihydrochloride
  • Vasodilator Agents / adverse effects*
  • Vocal Cords / drug effects
  • Vocal Cords / pathology*

Substances

  • Adrenal Cortex Hormones
  • Imidazoles
  • Phosphodiesterase Inhibitors
  • Piperazines
  • Sulfones
  • Triazines
  • Vasodilator Agents
  • Vardenafil Dihydrochloride